Perspective on nanoparticle technology for biomedical use

Ramesh Raliya, Tandeep Singh Chadha, Kelsey Haddad, Pratim Biswas

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations

Abstract

This review gives a short overview on the widespread use of nanostructured and nanocomposite materials for disease diagnostics, drug delivery, imaging and biomedical sensing applications. Nanoparticle interaction with a biological matrix/entity is greatly influenced by its morphology, crystal phase, surface chemistry, functionalization, physicochemical and electronic properties of the particle. Various nanoparticle synthesis routes, characterization, and functionalization methodologies to be used for biomedical applications ranging from drug delivery to molecular probing of underlying mechanisms and concepts are described with several examples (150 references).

Original languageEnglish (US)
Pages (from-to)2481-2490
Number of pages10
JournalCurrent pharmaceutical design
Volume22
Issue number17
DOIs
StatePublished - May 1 2016
Externally publishedYes

Keywords

  • Nanoparticles
  • Surface functionalization
  • Synthesis
  • Therapeutic application

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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