Peripheral arterial disease

A systemic disease extending beyond the affected extremity

Daniel G. Federman, Dawn M. Bravata, Robert Kirsner

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Peripheral arterial disease (PAD) is a manifestation of the atherosclerotic process and is associated with an increased risk of cerebrovascular disease, cardiovascular disease, and death. Clinicians should consider screening, both asymptomatic and symptomatic patients with the ankle-brachial index, a test with a high sensitivity and specificity. For those patients with PAD, atherosclerotic risk factors (such as smoking, dyslipidemia, hypertension, and diabetes mellitus) should be aggressively treated. In addition to exercise therapy, there is evidence available to support the use of aspirin, clopidogrel, lipid-lowering agents, pentoxifylline, and cilostazol.

Original languageEnglish
Pages (from-to)26-36
Number of pages11
JournalGeriatrics
Volume59
Issue number4
StatePublished - Apr 1 2004

Fingerprint

clopidogrel
Peripheral Arterial Disease
Extremities
Cerebrovascular Disorders
Exercise Therapy
Ankle Brachial Index
Pentoxifylline
Dyslipidemias
Aspirin
Diabetes Mellitus
Cardiovascular Diseases
Smoking
Hypertension
Lipids
Sensitivity and Specificity
cilostazol

Keywords

  • Ankle-brachial Index
  • Cardiovascular disease
  • Cerebrovascular disease
  • Peripheral vascular diseases
  • Smoking

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Peripheral arterial disease : A systemic disease extending beyond the affected extremity. / Federman, Daniel G.; Bravata, Dawn M.; Kirsner, Robert.

In: Geriatrics, Vol. 59, No. 4, 01.04.2004, p. 26-36.

Research output: Contribution to journalArticle

Federman, Daniel G. ; Bravata, Dawn M. ; Kirsner, Robert. / Peripheral arterial disease : A systemic disease extending beyond the affected extremity. In: Geriatrics. 2004 ; Vol. 59, No. 4. pp. 26-36.
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