Abstract
OBJECTIVE: To assess reproducibility of quadrantic and clock hour sectors of retinal nerve fiber layer thickness in normal eyes using optical coherence tomography. MATERIALS AND METHODS: Normal eyes of healthy volunteers meeting eligibility criteria were imaged by two inexperienced operators. Six 360° circular scans with a diameter of 3.4 mm centered on the optic disc were obtained during each scanning session, and a baseline image was formed using 3 high-quality images defined by the software. Images were obtained on three different days within a 4-week period. Variance and coefficient of variation (CV) were calculated for quadrantic and retinal nerve fiber layer clock hour sectors obtained from the baseline image. RESULTS: Five normal eyes were scanned. Intraoperator reproducibility was high. The mean (±SD) CV for total retinal nerve fiber layer thickness was 5.3±3.82% and 4.33±3.7% for operators 1 and 2, respectively. Interoperator reproducibility was good with statistically similar variance for all quadrantic and clock hour retinal nerve fiber layer parameters (P=.42 to .99). The nasal retinal nerve fiber layer was the most variable sector for both operators (mean CV: 10.42% and 7.83% for operators 1 and 2, respectively). Differences in mean total, nasal, temporal, and superior retinal nerve fiber layer thickness were not statistically significant between operators for all eyes; however, for inferior retinal nerve fiber layer thickness, there was a significant (P=.0007) difference between operators in one eye. CONCLUSION: Peripapillary retinal nerve fiber layer thickness assessments using optical coherence tomography have good intraoperator and interoperator reproducibility. Inexperienced operators can generate useful measurement data with acceptable levels of variance.
| Original language | English |
|---|---|
| Pages (from-to) | 33-37 |
| Number of pages | 5 |
| Journal | Ophthalmic Surgery and Lasers |
| Volume | 34 |
| Issue number | 1 |
| State | Published - Jan 1 2003 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
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Peripapillary nerve fiber layer thickness measurement reproducibility using optical coherence tomography. / Villain, Max A.; Greenfield, David.
In: Ophthalmic Surgery and Lasers, Vol. 34, No. 1, 01.01.2003, p. 33-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peripapillary nerve fiber layer thickness measurement reproducibility using optical coherence tomography
AU - Villain, Max A.
AU - Greenfield, David
PY - 2003/1/1
Y1 - 2003/1/1
N2 - OBJECTIVE: To assess reproducibility of quadrantic and clock hour sectors of retinal nerve fiber layer thickness in normal eyes using optical coherence tomography. MATERIALS AND METHODS: Normal eyes of healthy volunteers meeting eligibility criteria were imaged by two inexperienced operators. Six 360° circular scans with a diameter of 3.4 mm centered on the optic disc were obtained during each scanning session, and a baseline image was formed using 3 high-quality images defined by the software. Images were obtained on three different days within a 4-week period. Variance and coefficient of variation (CV) were calculated for quadrantic and retinal nerve fiber layer clock hour sectors obtained from the baseline image. RESULTS: Five normal eyes were scanned. Intraoperator reproducibility was high. The mean (±SD) CV for total retinal nerve fiber layer thickness was 5.3±3.82% and 4.33±3.7% for operators 1 and 2, respectively. Interoperator reproducibility was good with statistically similar variance for all quadrantic and clock hour retinal nerve fiber layer parameters (P=.42 to .99). The nasal retinal nerve fiber layer was the most variable sector for both operators (mean CV: 10.42% and 7.83% for operators 1 and 2, respectively). Differences in mean total, nasal, temporal, and superior retinal nerve fiber layer thickness were not statistically significant between operators for all eyes; however, for inferior retinal nerve fiber layer thickness, there was a significant (P=.0007) difference between operators in one eye. CONCLUSION: Peripapillary retinal nerve fiber layer thickness assessments using optical coherence tomography have good intraoperator and interoperator reproducibility. Inexperienced operators can generate useful measurement data with acceptable levels of variance.
AB - OBJECTIVE: To assess reproducibility of quadrantic and clock hour sectors of retinal nerve fiber layer thickness in normal eyes using optical coherence tomography. MATERIALS AND METHODS: Normal eyes of healthy volunteers meeting eligibility criteria were imaged by two inexperienced operators. Six 360° circular scans with a diameter of 3.4 mm centered on the optic disc were obtained during each scanning session, and a baseline image was formed using 3 high-quality images defined by the software. Images were obtained on three different days within a 4-week period. Variance and coefficient of variation (CV) were calculated for quadrantic and retinal nerve fiber layer clock hour sectors obtained from the baseline image. RESULTS: Five normal eyes were scanned. Intraoperator reproducibility was high. The mean (±SD) CV for total retinal nerve fiber layer thickness was 5.3±3.82% and 4.33±3.7% for operators 1 and 2, respectively. Interoperator reproducibility was good with statistically similar variance for all quadrantic and clock hour retinal nerve fiber layer parameters (P=.42 to .99). The nasal retinal nerve fiber layer was the most variable sector for both operators (mean CV: 10.42% and 7.83% for operators 1 and 2, respectively). Differences in mean total, nasal, temporal, and superior retinal nerve fiber layer thickness were not statistically significant between operators for all eyes; however, for inferior retinal nerve fiber layer thickness, there was a significant (P=.0007) difference between operators in one eye. CONCLUSION: Peripapillary retinal nerve fiber layer thickness assessments using optical coherence tomography have good intraoperator and interoperator reproducibility. Inexperienced operators can generate useful measurement data with acceptable levels of variance.
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M3 - Article
C2 - 12570002
AN - SCOPUS:0037247486
VL - 34
SP - 33
EP - 37
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
SN - 2325-8160
IS - 1
ER -