Tratamento de rugas periorbitais por terapia de indução de colágeno

Translated title of the contribution: Periorbital wrinkles treatment using collagen induction therapy

Gabriella Fabbrocini, Maria Pia De Padova, Valerio De Vita, Nunzio Fardella, Francesco Pastore, Antonella Tosti

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Introduction: Periorbital wrinkles are very common cutaneous folds, that develop on the periocular area. The treatment for wrinkles varies with the degree of severity. A relatively new treatment, termed Collagen Induction Therapy (CIT) seems to be appropriate for the treatment of periorbital wrinkles. Objective: To confi rm the usefulness of CIT in periorbital wrinkles treatment. Patients and methods: In total, 20 patients (12 females, 8 males; between 50-65 years of age) with periorbital wrinkles were included. Each patient was treated with a specifi c tool in two sessions. Using digital cameras, photos of all patients were taken to evaluate wrinkles'depth and silicone rubber was used to make a microrelief impression of the wrinkles. The photographic data were analysed by using the sign test statistic (α < 0.05). Cutaneous casts' data were analysed by computerized image analysis. Results: Analysis of the patient photographs, supported by the sign test, and of the degree of irregularity of the surface microrelief, suppo rted by Fast Fourier Transform and by wrinkle's image processing, showed that, after only two sessions, the wrinkles' severity grade in most patients was greatly reduced. Conclusion: The present study suggests that CIT can be a suitable technique to improve periorbital wrinkles.

Translated title of the contributionPeriorbital wrinkles treatment using collagen induction therapy
Original languagePortuguese
Pages (from-to)106-111
Number of pages6
JournalSurgical and Cosmetic Dermatology
Issue number3
StatePublished - 2009
Externally publishedYes


  • Ambulatory surgery procedures
  • Collagen
  • Skin aging

ASJC Scopus subject areas

  • Dermatology
  • Surgery


Dive into the research topics of 'Periorbital wrinkles treatment using collagen induction therapy'. Together they form a unique fingerprint.

Cite this