Periodontal disease and incident prediabetes and diabetes: The Hispanic Community Health Study/Study of Latinos

Nadia Laniado, Tasneem Khambaty, Simin Hua, Robert Kaplan, Maria M. Llabre, Neil Schneiderman, Richard H. Singer, Qibin Qi, Jianwen Cai, Tracy L. Finlayson, Adam M. Whalen, Carmen R. Isasi

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To examine whether baseline periodontal disease is independently associated with incident prediabetes and incident diabetes in Hispanics/Latinos in the United States. Materials and Methods: This study examined 7827 individuals, 18–74 years of age without diabetes, from the Hispanic Community Health Study/Study of Latinos. Participants received a full-mouth periodontal examination at baseline (2008–2011), and the disease was classified using the Centers for Disease Control and Prevention/American Academy of Periodontology case definitions. At Visit 2 (2014–2017), incident prediabetes and diabetes were assessed using multiple standard procedures including blood tests. Multivariable survey Poisson regressions estimated the rate ratio (RR) and 95% confidence intervals (CIs) of incident prediabetes and incident diabetes associated with periodontal disease severity. Results: Among the individuals without prediabetes or diabetes at baseline, 38.8% (n = 1553) had developed prediabetes and 2.2% (n = 87) had developed diabetes after 6 years. Nineteen percent (n = 727) of individuals with prediabetes at baseline developed diabetes after 6 years. Adjusting for all potential confounders, no significant association was found between periodontal disease severity and either incident prediabetes (RR: 0.93; 95% CI: 0.82–1.06) or incident diabetes (RR: 0.99; 95% CI: 0.80–1.22). Conclusions: Our findings suggest that among a diverse cohort of Hispanic/Latino individuals living in the United States, there was no association between periodontal disease severity and the development of either prediabetes or diabetes during a 6-year follow-up period.

Original languageEnglish (US)
Pages (from-to)313-321
Number of pages9
JournalJournal of Clinical Periodontology
Volume49
Issue number4
DOIs
StatePublished - Apr 2022

Keywords

  • Hispanic Americans
  • diabetes mellitus
  • oral health
  • periodontal diseases
  • prediabetes
  • type 2 diabetes

ASJC Scopus subject areas

  • Periodontics

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