Performance of processes of care and outcomes in patients with Staphylococcus aureus bacteremia

Rossana Rosa, Andrew Wawrzyniak, Maroun Sfeir, Laura Smith, Lilian M. Abbo

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

BACKGROUND: Staphylococcus aureus bacteremia (SAB) is associated with significant morbidity and mortality in hospitalized adults. OBJECTIVE: We aimed to identify current practice patterns in the management of SAB, and to evaluate their association with clinical outcomes. DESIGN: Retrospective cohort study. SETTING: A 1558-bed tertiary care teaching hospital. PATIENTS: Adult patients hospitalized between January 1, 2012 through April 30, 2013, who had at least 1 positive blood culture with S aureus. INTERVENTION: None MEASUREMENTS: Electronic medical records were reviewed and the processes of care in the management of SAB were identified. The main outcome was clinical failure, defined as a composite endpoint of in-hospital mortality and persistent bacteremia. RESULTS: Two hundred fifty episodes of SAB occurred in 241 patients, and 78 (32.4%) had clinical failure. Processes of care that impacted the risk of clinical failure included: timing of follow-up blood cultures (delays of >4 days had a relative risk [RR] of 6.6; 95% confidence interval [CI]: 2.1-20.5; P=0.001), consultation with infectious diseases specialist within 6 days from diagnosis of SAB (RR: 0.3; 95% CI: 0.1-0.9; P=0.03), and use of β-lactams in patients with methicillin-susceptible S aureus bacteremia (RR: 0.1; 95% CI: 0.04-0.5; P=0.002). CONCLUSIONS: The processes of care identified in our study could serve as quality and patient safety indicators for the management of SAB.

Original languageEnglish (US)
Pages (from-to)27-32
Number of pages6
JournalJournal of Hospital Medicine
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Leadership and Management
  • Internal Medicine
  • Fundamentals and skills
  • Health Policy
  • Care Planning
  • Assessment and Diagnosis

Fingerprint Dive into the research topics of 'Performance of processes of care and outcomes in patients with Staphylococcus aureus bacteremia'. Together they form a unique fingerprint.

  • Cite this