Abstract
This case report documents a perforation of the terminal ileum in a 40-year-old white male homosexual with the acquired immunodeficiency syndrome. The perforation occurred at a site that had severe cytomegalovirus infection and was in close proximity to multiple nodules of Kaposi's sarcoma. The ileum showed multiple deep ulcers with large numbers of cytomegalovirus inclusions and vasculitis with infected endothelial cells, small-vessel thrombosis, focal disruption, and hemorrhage. We review the evidence that cytomegalovirus infection-and not Kaposi's sarcoma-was responsible for this perforation and, in light of the new medical therapy for such infections, should be regarded as an important cause of gastrointestinal perforation in patients with the acquired immunodeficiency syndrome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 540-545 |
| Number of pages | 6 |
| Journal | Surgery |
| Volume | 102 |
| Issue number | 3 |
| State | Published - 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
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Perforation of the terminal ileum with cytomegalovirus vasculitis and Kaposi's sarcoma in a patient with aquired immunodeficiency syndrome. / Burke, George W; Nichols, Larry; Balogh, Karoly; Hammer, Scott; Jensen, William; Pomposelli, Frank; Jenkins, Roger.
In: Surgery, Vol. 102, No. 3, 1987, p. 540-545.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Perforation of the terminal ileum with cytomegalovirus vasculitis and Kaposi's sarcoma in a patient with aquired immunodeficiency syndrome
AU - Burke, George W
AU - Nichols, Larry
AU - Balogh, Karoly
AU - Hammer, Scott
AU - Jensen, William
AU - Pomposelli, Frank
AU - Jenkins, Roger
PY - 1987
Y1 - 1987
N2 - This case report documents a perforation of the terminal ileum in a 40-year-old white male homosexual with the acquired immunodeficiency syndrome. The perforation occurred at a site that had severe cytomegalovirus infection and was in close proximity to multiple nodules of Kaposi's sarcoma. The ileum showed multiple deep ulcers with large numbers of cytomegalovirus inclusions and vasculitis with infected endothelial cells, small-vessel thrombosis, focal disruption, and hemorrhage. We review the evidence that cytomegalovirus infection-and not Kaposi's sarcoma-was responsible for this perforation and, in light of the new medical therapy for such infections, should be regarded as an important cause of gastrointestinal perforation in patients with the acquired immunodeficiency syndrome.
AB - This case report documents a perforation of the terminal ileum in a 40-year-old white male homosexual with the acquired immunodeficiency syndrome. The perforation occurred at a site that had severe cytomegalovirus infection and was in close proximity to multiple nodules of Kaposi's sarcoma. The ileum showed multiple deep ulcers with large numbers of cytomegalovirus inclusions and vasculitis with infected endothelial cells, small-vessel thrombosis, focal disruption, and hemorrhage. We review the evidence that cytomegalovirus infection-and not Kaposi's sarcoma-was responsible for this perforation and, in light of the new medical therapy for such infections, should be regarded as an important cause of gastrointestinal perforation in patients with the acquired immunodeficiency syndrome.
UR - http://www.scopus.com/inward/record.url?scp=0023615491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023615491&partnerID=8YFLogxK
M3 - Article
C2 - 2820074
AN - SCOPUS:0023615491
VL - 102
SP - 540
EP - 545
JO - Surgery (United States)
JF - Surgery (United States)
SN - 0039-6060
IS - 3
ER -