Percutaneous ultrasound-guided sclerotherapy for complicated fetal intralobar bronchopulmonary sequestration

C. Bermúdez, J. Pérez-Wulff, G. Bufalino, C. Sosa, L. Gómez, R. A. Quintero

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Bronchopulmonary sequestration (BPS), which can be intralobar or extralobar, is a rare developmental anomaly of the lung characterized by nonfunctional pulmonary tissue without communication with the tracheobronchial tree and with an aberrant systemic arterial blood supply. The intralobar type is typically within the pleural cavity with an arterial feeding vessel generally arising from the thoracic aorta and with venous drainage into the left atrium. The prognosis is poor in cases diagnosed before 26 weeks' gestation and when there is mediastinal shift, polyhydramnios and fetal hydrops. The ideal prenatal management option remains undefined. We present a series of three complicated cases of intralobar BPS treated prenatally with percutaneous ultrasound-guided fetal sclerotherapy (FST). The feeding vessel was successfully accessed percutaneously under ultrasound guidance in all cases. FST with polidocanol resulted in complete obliteration of the blood flow to the mass. Abnormal Doppler findings, ascites, hydrops and polyhydramnios resolved and all patients were delivered at term. Antenatal treatment of patients with complicated BPS can be successfully achieved with FST, which is a simple and inexpensive technique. Comparison of risks and benefits of this approach with other techniques is warranted.

Original languageEnglish
Pages (from-to)586-589
Number of pages4
JournalUltrasound in Obstetrics and Gynecology
Volume29
Issue number5
DOIs
StatePublished - May 1 2007

Fingerprint

Bronchopulmonary Sequestration
Sclerotherapy
Polyhydramnios
vessels
aorta
prognosis
blood flow
drainage
lungs
blood
Hydrops Fetalis
Pleural Cavity
Lung
communication
anomalies
Heart Atria
Thoracic Aorta
Ascites
cavities
Drainage

Keywords

  • Fetal hydrops
  • Fetal therapy
  • Lung mass
  • Polidocanol
  • Pulmonary sequestration
  • Sclerotherapy

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

Cite this

Percutaneous ultrasound-guided sclerotherapy for complicated fetal intralobar bronchopulmonary sequestration. / Bermúdez, C.; Pérez-Wulff, J.; Bufalino, G.; Sosa, C.; Gómez, L.; Quintero, R. A.

In: Ultrasound in Obstetrics and Gynecology, Vol. 29, No. 5, 01.05.2007, p. 586-589.

Research output: Contribution to journalArticle

Bermúdez, C. ; Pérez-Wulff, J. ; Bufalino, G. ; Sosa, C. ; Gómez, L. ; Quintero, R. A. / Percutaneous ultrasound-guided sclerotherapy for complicated fetal intralobar bronchopulmonary sequestration. In: Ultrasound in Obstetrics and Gynecology. 2007 ; Vol. 29, No. 5. pp. 586-589.
@article{d738c80e204b488aa9ec25c491495b34,
title = "Percutaneous ultrasound-guided sclerotherapy for complicated fetal intralobar bronchopulmonary sequestration",
abstract = "Bronchopulmonary sequestration (BPS), which can be intralobar or extralobar, is a rare developmental anomaly of the lung characterized by nonfunctional pulmonary tissue without communication with the tracheobronchial tree and with an aberrant systemic arterial blood supply. The intralobar type is typically within the pleural cavity with an arterial feeding vessel generally arising from the thoracic aorta and with venous drainage into the left atrium. The prognosis is poor in cases diagnosed before 26 weeks' gestation and when there is mediastinal shift, polyhydramnios and fetal hydrops. The ideal prenatal management option remains undefined. We present a series of three complicated cases of intralobar BPS treated prenatally with percutaneous ultrasound-guided fetal sclerotherapy (FST). The feeding vessel was successfully accessed percutaneously under ultrasound guidance in all cases. FST with polidocanol resulted in complete obliteration of the blood flow to the mass. Abnormal Doppler findings, ascites, hydrops and polyhydramnios resolved and all patients were delivered at term. Antenatal treatment of patients with complicated BPS can be successfully achieved with FST, which is a simple and inexpensive technique. Comparison of risks and benefits of this approach with other techniques is warranted.",
keywords = "Fetal hydrops, Fetal therapy, Lung mass, Polidocanol, Pulmonary sequestration, Sclerotherapy",
author = "C. Berm{\'u}dez and J. P{\'e}rez-Wulff and G. Bufalino and C. Sosa and L. G{\'o}mez and Quintero, {R. A.}",
year = "2007",
month = "5",
day = "1",
doi = "10.1002/uog.3944",
language = "English",
volume = "29",
pages = "586--589",
journal = "Ultrasound in Obstetrics and Gynecology",
issn = "0960-7692",
publisher = "John Wiley and Sons Ltd",
number = "5",

}

TY - JOUR

T1 - Percutaneous ultrasound-guided sclerotherapy for complicated fetal intralobar bronchopulmonary sequestration

AU - Bermúdez, C.

AU - Pérez-Wulff, J.

AU - Bufalino, G.

AU - Sosa, C.

AU - Gómez, L.

AU - Quintero, R. A.

PY - 2007/5/1

Y1 - 2007/5/1

N2 - Bronchopulmonary sequestration (BPS), which can be intralobar or extralobar, is a rare developmental anomaly of the lung characterized by nonfunctional pulmonary tissue without communication with the tracheobronchial tree and with an aberrant systemic arterial blood supply. The intralobar type is typically within the pleural cavity with an arterial feeding vessel generally arising from the thoracic aorta and with venous drainage into the left atrium. The prognosis is poor in cases diagnosed before 26 weeks' gestation and when there is mediastinal shift, polyhydramnios and fetal hydrops. The ideal prenatal management option remains undefined. We present a series of three complicated cases of intralobar BPS treated prenatally with percutaneous ultrasound-guided fetal sclerotherapy (FST). The feeding vessel was successfully accessed percutaneously under ultrasound guidance in all cases. FST with polidocanol resulted in complete obliteration of the blood flow to the mass. Abnormal Doppler findings, ascites, hydrops and polyhydramnios resolved and all patients were delivered at term. Antenatal treatment of patients with complicated BPS can be successfully achieved with FST, which is a simple and inexpensive technique. Comparison of risks and benefits of this approach with other techniques is warranted.

AB - Bronchopulmonary sequestration (BPS), which can be intralobar or extralobar, is a rare developmental anomaly of the lung characterized by nonfunctional pulmonary tissue without communication with the tracheobronchial tree and with an aberrant systemic arterial blood supply. The intralobar type is typically within the pleural cavity with an arterial feeding vessel generally arising from the thoracic aorta and with venous drainage into the left atrium. The prognosis is poor in cases diagnosed before 26 weeks' gestation and when there is mediastinal shift, polyhydramnios and fetal hydrops. The ideal prenatal management option remains undefined. We present a series of three complicated cases of intralobar BPS treated prenatally with percutaneous ultrasound-guided fetal sclerotherapy (FST). The feeding vessel was successfully accessed percutaneously under ultrasound guidance in all cases. FST with polidocanol resulted in complete obliteration of the blood flow to the mass. Abnormal Doppler findings, ascites, hydrops and polyhydramnios resolved and all patients were delivered at term. Antenatal treatment of patients with complicated BPS can be successfully achieved with FST, which is a simple and inexpensive technique. Comparison of risks and benefits of this approach with other techniques is warranted.

KW - Fetal hydrops

KW - Fetal therapy

KW - Lung mass

KW - Polidocanol

KW - Pulmonary sequestration

KW - Sclerotherapy

UR - http://www.scopus.com/inward/record.url?scp=34249718823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249718823&partnerID=8YFLogxK

U2 - 10.1002/uog.3944

DO - 10.1002/uog.3944

M3 - Article

C2 - 17444552

AN - SCOPUS:34249718823

VL - 29

SP - 586

EP - 589

JO - Ultrasound in Obstetrics and Gynecology

JF - Ultrasound in Obstetrics and Gynecology

SN - 0960-7692

IS - 5

ER -