Percutaneous pulmonary valve implantation: Present status and evolving future

Mohammad M. Ansari, Rhanderson Cardoso, Daniel Garcia, Satinder Sandhu, Eric Horlick, Derek Brinster, Giuseppe Martucci, Nicolo Piazza

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Due to recurrent right ventricular outflow tract (RVOT) dysfunction, patients with complex congenital heart disease of the RVOT traditionally require multiple surgical interventions during their lifetimes. Percutaneous pulmonary valve implantation (PPVI) has been developed as a nonsurgical alternative for the treatment of right ventricular to pulmonary artery stenosis or pulmonary regurgitation. PPVI has been shown to be a safe and effective procedure in patients with dysfunctional surgical RVOT conduits. In this population, PPVI has the potential to improve symptoms, functional capacity, and biventricular hemodynamics. However, limitations to the anatomical substrate and size of the RVOT currently restrict PPVI eligibility to less than one-quarter of patients with RVOT dysfunction. The current review discusses contemporary practices in PPVI, evidence supporting the procedure, and future technologies and developments in the field.

Original languageEnglish (US)
Pages (from-to)2246-2255
Number of pages10
JournalJournal of the American College of Cardiology
Issue number20
StatePublished - Nov 17 2015


  • congenital heart disease
  • outcome assessment (health care)
  • pulmonary regurgitation
  • right ventricular outflow tract dysfunction
  • transcatheter pulmonary valve

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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