Peptides and Psychoneuroendocrinology: A Perspective

Charles B. Nemeroff, Arthur J. Prange

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Research indicates that brain peptides exert both behavioral and endocrinologic effects in humans and animals. This review summarizes the best known behavioral actions of four endogenous peptides: luteinizing hormone releasing hormone (LHRH), adrenocorticotrophic hormone (ACTH), vasopressin, and angiotensin. The hypothalamic releasing hormones play a role in modulating pituitary end organ systems. Behavioral disorders may, in the future, be susceptible to formulation in terms of changes in brain peptides. Peptide research in psychiatry may be approached in several ways.

Original languageEnglish (US)
Pages (from-to)999-1010
Number of pages12
JournalArchives of General Psychiatry
Issue number8
StatePublished - Aug 1978
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health


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