Pediatric suprasellar tumors

Heather J. McCrea, Emilie George, Allison Settler, Theodore H. Schwartz, Jeffrey P. Greenfield

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

The various childhood suprasellar tumors, while pathologically distinct, present similar clinical and surgical challenges as a result of their common anatomic location. These lesions are in close proximity to or may invade the optic nerve and chiasm, pituitary gland and infundibulum, hypothalamus, and third ventricle, leading to presenting features including visual field loss, impairment in visual acuity, endocrine dysfunction, and hydrocephalus. Though many suprasellar lesions are relatively benign in pathology, treatment may be complicated by high surgical morbidity resulting from damage to the hypothalamic-pituitary axis. Here we review the most frequent pediatric lesions occurring in the suprasellar region: craniopharyngioma, chiasmatic glioma, germ cell tumor, Rathke cleft and arachnoid cysts, pituitary adenoma, and histiocytosis. This review outlines both common presenting features and differentiating aspects of these lesions. It also includes classic radiographic presentations and treatment considerations for each lesion.

Original languageEnglish (US)
Pages (from-to)1367-1376
Number of pages10
JournalJournal of child neurology
Volume31
Issue number12
DOIs
StatePublished - Oct 1 2016
Externally publishedYes

Keywords

  • craniopharyngioma
  • neurosurgery
  • pediatric
  • suprasellar tumors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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