Pediatric depression: Neurocognitive function and treatment implications

Jennifer C. Britton, Sarah M. Kennedy, Ilana Seager, Alexander H. Queen, Michael V. Hernandez, Carolyn N. Spiro, Jill Ehrenreich-May

Research output: Chapter in Book/Report/Conference proceedingChapter


Major depressive disorder (MDD) is common in children and adolescents, affecting up to 2 percent of children and 4 percent to 7 percent of adolescents in a given year (Costello et al., 2002). Pediatric depression negatively impacts mood, self-esteem, and daily functioning. For example, children may experience persistent sad mood, irritability, increased feelings of hopelessness, or disturbances in sleep and appetite (American Psychiatric Association, Association, 2013). The onset of MDD increases during adolescence, as compared to lower prevalence rates observed among younger children (Kessler, Avenevoli, & Ries Merikangas, 2001; Lewinsohn, Clarke, Seeley, & Rohde, 1994). Before reaching adulthood, approximately 20 percent of adolescents will have been diagnosed with MDD (Birmaher, Ryan, Williamson, Brent, & Kaufman, 1996; Birmaher, Ryan, Williamson, Brent, Kaufman, et al., 1996).

Original languageEnglish (US)
Title of host publicationFrom Symptom to Synapse
Subtitle of host publicationA Neurocognitive Perspective on Clinical Psychology
PublisherTaylor and Francis
Number of pages36
ISBN (Electronic)9781135046675
ISBN (Print)9780415835862
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Psychology(all)


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