Patterns of increased intracranial pressure after severe traumatic brain injury

Kristine H O'Phelan, Dalnam Park, Jimmy T. Efird, Katherine Johnson, Melanie Albano, Juliet Beniga, Deborah M. Green, Cherylee W J Chang

Research output: Contribution to journalArticle

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Abstract

Introduction: Secondary brain injury due to increased intracranial pressure (ICP) contributes to post-traumatic morbidity and mortality. Although it is often taught that increased ICP begins early after traumatic brain injury, some patients develop increased ICP after the first 3 days post-injury. We examined our data to describe temporal patterns of increased ICP. Methods: This is a retrospective review of prospectively collected physiologic and demographic data. Results: Seventy-seven patients were included. We identified four patterns of increased ICP: beginning within 72 h (early), beginning after 72 h (late), early increases with resolution, and then a second rise after 72 h (bimodal), and continuously increased ICP. Late increases in ICP occur in 17% of this cohort. Peak day of swelling was day 7 for the "late" rise group and day 4 for the other patients with increased ICP. Forty-four percent of patients showed enlargement of cerebral contusions on follow-up imaging at 24 h post-injury. Conclusions: Late rises in ICP were not rare in this cohort. This is clinically relevant as it may impact decisions about ICP monitor removal. Differences between groups in age, CT patterns of injury, fluid therapy, osmotic use, and fever were not statistically significant.

Original languageEnglish
Pages (from-to)280-286
Number of pages7
JournalNeurocritical Care
Volume10
Issue number3
DOIs
StatePublished - Jun 1 2009

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Intracranial Pressure
Wounds and Injuries
Traumatic Brain Injury
Intracranial Hypertension
Fluid Therapy
Brain Injuries
Fever
Age Groups
Demography
Morbidity
Mortality

Keywords

  • Intracranial hypertension
  • Intracranial pressure
  • Traumatic brain injury

ASJC Scopus subject areas

  • Clinical Neurology
  • Critical Care and Intensive Care Medicine

Cite this

O'Phelan, K. H., Park, D., Efird, J. T., Johnson, K., Albano, M., Beniga, J., ... Chang, C. W. J. (2009). Patterns of increased intracranial pressure after severe traumatic brain injury. Neurocritical Care, 10(3), 280-286. https://doi.org/10.1007/s12028-008-9183-7

Patterns of increased intracranial pressure after severe traumatic brain injury. / O'Phelan, Kristine H; Park, Dalnam; Efird, Jimmy T.; Johnson, Katherine; Albano, Melanie; Beniga, Juliet; Green, Deborah M.; Chang, Cherylee W J.

In: Neurocritical Care, Vol. 10, No. 3, 01.06.2009, p. 280-286.

Research output: Contribution to journalArticle

O'Phelan, KH, Park, D, Efird, JT, Johnson, K, Albano, M, Beniga, J, Green, DM & Chang, CWJ 2009, 'Patterns of increased intracranial pressure after severe traumatic brain injury', Neurocritical Care, vol. 10, no. 3, pp. 280-286. https://doi.org/10.1007/s12028-008-9183-7
O'Phelan, Kristine H ; Park, Dalnam ; Efird, Jimmy T. ; Johnson, Katherine ; Albano, Melanie ; Beniga, Juliet ; Green, Deborah M. ; Chang, Cherylee W J. / Patterns of increased intracranial pressure after severe traumatic brain injury. In: Neurocritical Care. 2009 ; Vol. 10, No. 3. pp. 280-286.
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