Patterns of acute inferior wall myocardial infarction caused by hyperkalemia

J. A. Pastor, Agustin Castellanos, F. Moleiro, Robert J Myerburg

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

This is one of the first published articles dealing with two patients with hyperkalemia showing, not only a pattern of acute anteroseptal myocardial infarction, but of inferior myocardial infarction as well. This was attributed to uneven effects of high potassium in different regions of the heart. Marked reduction of resting potential of a large group of cells from the most affected regions could produce areas of inexcitability, capable of generating abnormal q waves. Likewise, ST-segment elevation could be attributed to a hyperkalemic diastolic current of injury (due to depolarization of resting potential) and to a combination of diastolic and systolic current of injury (due to a reduction of action potential amplitude). In addition, current flowing down voltage gradients on either side (epicardial and endocardial) of the M cell region could be responsible for the T wave, and even, to some extent, to the ST-segment changes. However, it cannot be excluded that the previously described changes may have resulted from coronary spasm without chest pain. In fact, an intriguing possibility, namely that hyperkalemia could trigger coronary spasm has to be considered also.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalJournal of Electrocardiology
Volume34
Issue number1
DOIs
StatePublished - Mar 24 2001

Fingerprint

Inferior Wall Myocardial Infarction
Hyperkalemia
Spasm
Membrane Potentials
Anterior Wall Myocardial Infarction
Wounds and Injuries
Chest Pain
Action Potentials
Potassium

Keywords

  • Action potentials
  • Dialyzable current of injury
  • Hyperkalemia
  • Hypocalcemia
  • Myocardial infarction
  • QT interval

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Patterns of acute inferior wall myocardial infarction caused by hyperkalemia. / Pastor, J. A.; Castellanos, Agustin; Moleiro, F.; Myerburg, Robert J.

In: Journal of Electrocardiology, Vol. 34, No. 1, 24.03.2001, p. 53-58.

Research output: Contribution to journalArticle

Pastor, J. A. ; Castellanos, Agustin ; Moleiro, F. ; Myerburg, Robert J. / Patterns of acute inferior wall myocardial infarction caused by hyperkalemia. In: Journal of Electrocardiology. 2001 ; Vol. 34, No. 1. pp. 53-58.
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