Abstract
Objective: to better characterize the properties of chromatic pattern Electroretinograms (ChPERGs) and establish normative value for a set of stimuli able to elicit robust and reliable responses, suitable for clinical application in neurological disorders. Materials and methods: PERGs were recorded in response to both equiluminant red-green (R-G) and blue-yellow (B-Y) as well as luminance (Lum) contrast stimuli (yellow-black, Y-Bk), known to emphasize activity of the parvo-, konio- and magnocellular ganglion-cell subsystem respectively. Results: PERG responses could be reliably recorded either in normal observers as well in patients and signal were reproducible. Responses exhibited a typical positive-negative (P1-N1) waveform for both R-G and B-Y stimuli and had a smaller amplitude and a longer latency that Lum ones. Conclusions: these results complement previous studies aimed at characterizing the properties of ChPERGs; in addition normative data are provided for a set of stimulus characteristics suitable for the clinical routine; furthermore pathognomonic changes in main neurological diseases are reported.
Original language | English (US) |
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Pages (from-to) | 4-7 |
Number of pages | 4 |
Journal | Internal Medicine Clinical and Laboratory |
Volume | 13-14 |
Issue number | 1-3 |
State | Published - Jan 1 2005 |
Keywords
- Chromatic contrast
- Idiopathic Parkinson's disease
- konio- and magnocellulare subsystem
- Luminance contrast
- Multiple sclerosis
- Multiple system atrophy
- Parvo-
- Pattern electroretinogram
ASJC Scopus subject areas
- Internal Medicine