Abstract
Onychomycosis is a difficult diagnosis to manage and treatment is sometimes avoided, as this diagnosis is often wrongly perceived as a cosmetic problem. However, onychomycosis has a negative impact on patients’ quality of life, affecting social interaction, psychological well-being, and physical activities. Onychomycosis is also a risk factor for patients with diabetes, with proven increased rates of cellulitis, gangrene, and foot ulcers. Treatments are only mild to moderately effective, and rates of relapse and reinfection are high. Oral treatments require laboratory monitoring due to risk of hepatotoxicity and may be contraindicated in some patients due to risk of drug–drug interactions. Topical treatments require prolonged application and are not very effective. Efinaconazole 10% solution is a new topical triazole treatment for mild to moderate distal subungual onychomycosis, with good efficacy and without the need for debridement of nails. In onychomycosis of the toenails, efinaconazole 10% solution is documented to have a statistically significant, positive impact on patient satisfaction and quality of life.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 887-891 |
| Number of pages | 5 |
| Journal | Patient Preference and Adherence |
| Volume | 9 |
| DOIs | |
| State | Published - Jun 30 2015 |
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Keywords
- Antifungal
- Dermatophyte
- Fungus
- Nail
- Quality of life
- Treatment
ASJC Scopus subject areas
- Social Sciences (miscellaneous)
- Medicine (miscellaneous)
- Health Policy
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Cite this
Patient considerations in the management of toe onychomycosis – Role of efinaconazole. / LaSenna, Charlotte E.; Tosti, Antonella.
In: Patient Preference and Adherence, Vol. 9, 30.06.2015, p. 887-891.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Patient considerations in the management of toe onychomycosis – Role of efinaconazole
AU - LaSenna, Charlotte E.
AU - Tosti, Antonella
PY - 2015/6/30
Y1 - 2015/6/30
N2 - Onychomycosis is a difficult diagnosis to manage and treatment is sometimes avoided, as this diagnosis is often wrongly perceived as a cosmetic problem. However, onychomycosis has a negative impact on patients’ quality of life, affecting social interaction, psychological well-being, and physical activities. Onychomycosis is also a risk factor for patients with diabetes, with proven increased rates of cellulitis, gangrene, and foot ulcers. Treatments are only mild to moderately effective, and rates of relapse and reinfection are high. Oral treatments require laboratory monitoring due to risk of hepatotoxicity and may be contraindicated in some patients due to risk of drug–drug interactions. Topical treatments require prolonged application and are not very effective. Efinaconazole 10% solution is a new topical triazole treatment for mild to moderate distal subungual onychomycosis, with good efficacy and without the need for debridement of nails. In onychomycosis of the toenails, efinaconazole 10% solution is documented to have a statistically significant, positive impact on patient satisfaction and quality of life.
AB - Onychomycosis is a difficult diagnosis to manage and treatment is sometimes avoided, as this diagnosis is often wrongly perceived as a cosmetic problem. However, onychomycosis has a negative impact on patients’ quality of life, affecting social interaction, psychological well-being, and physical activities. Onychomycosis is also a risk factor for patients with diabetes, with proven increased rates of cellulitis, gangrene, and foot ulcers. Treatments are only mild to moderately effective, and rates of relapse and reinfection are high. Oral treatments require laboratory monitoring due to risk of hepatotoxicity and may be contraindicated in some patients due to risk of drug–drug interactions. Topical treatments require prolonged application and are not very effective. Efinaconazole 10% solution is a new topical triazole treatment for mild to moderate distal subungual onychomycosis, with good efficacy and without the need for debridement of nails. In onychomycosis of the toenails, efinaconazole 10% solution is documented to have a statistically significant, positive impact on patient satisfaction and quality of life.
KW - Antifungal
KW - Dermatophyte
KW - Fungus
KW - Nail
KW - Quality of life
KW - Treatment
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UR - http://www.scopus.com/inward/citedby.url?scp=84936937643&partnerID=8YFLogxK
U2 - 10.2147/PPA.S72701
DO - 10.2147/PPA.S72701
M3 - Article
AN - SCOPUS:84936937643
VL - 9
SP - 887
EP - 891
JO - Patient Preference and Adherence
JF - Patient Preference and Adherence
SN - 1177-889X
ER -