Patient alignment and target tracking in radiosurgery of soft-tissue tumors using combined fiducial and skeletal structures tracking techniques

Xiaodong Wu, Dongshan Fu, Alberto De La Zerda, Elizabeth Bossart, Hua Shao, Joseph Both, Walter Nikesch, Zhicong Huang, Arnold Markoe, James G. Schwade

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

When using the CyberKnife® (Accuray Incorporated, Sunnyvale, CA) Image-Guided Stereotactic Radiosurgery (SRS) System to treat soft-tissue tumors in anatomic sites other than intracranial or spinal locations - such as in the lung, liver, kidney, prostate, and pancreas - fiducial placement in or close to the tumors is necessary to assist patient alignment and target tracking for precise treatment delivery. Under the assumption of rigid transformation, at least three fiducial markers are required to obtain six-degreesof-freedom transformation parameters, i.e., three translations and three rotations. However, in most cases, soft tissue is highly deformable and non-rigid. This results in three possible scenarios: 1) the rigid body criteria fail and the rotational transformation cannot be obtained, 2) the tumor deformation results in unreliable computed rotational information, and 3) even when the fiducial array meets the rigid body criteria, the orientation of the tumor often has poor correlation with the global body orientation and thus results in dosimetric deviation.

Original languageEnglish
Title of host publicationTreating Tumors that Move with Respiration
PublisherSpringer Berlin Heidelberg
Pages31-36
Number of pages6
ISBN (Print)9783540698852
DOIs
StatePublished - Dec 1 2007

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wu, X., Fu, D., De La Zerda, A., Bossart, E., Shao, H., Both, J., Nikesch, W., Huang, Z., Markoe, A., & Schwade, J. G. (2007). Patient alignment and target tracking in radiosurgery of soft-tissue tumors using combined fiducial and skeletal structures tracking techniques. In Treating Tumors that Move with Respiration (pp. 31-36). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-69886-9_3