Pathophysiology of cardiac extracorporeal membrane oxygenation

Bradley P. Fuhrman, Lynn J. Hernan, Alexandre T. Rotta, Christopher M.B. Heard, Eliot R. Rosenkranz

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The treatment of cardiogenic shock using inotropic agents and vascular volume expansion places an added burden on the heart. The resultant increase in cardiac work may cause myocardial ischemia and lead to cardiac arrest. Extracorporeal membrane oxygenation (ECMO) may be used to treat cardiogenic shock. It supports systemic circulation, assures diastolic perfusion of the myocardium, and reduces cardiac workload. The rise in blood pressure associated with restoring systemic circulation afterloads the heart and can cause left atrial hypertension and pulmonary edema. ECMO does not automatically reduce cardiac work, especially in the presence of residual shunts. Left atrial drainage or decompression may be essential in certain patients both to avert pulmonary edema and to reduce cardiac work.

Original languageEnglish (US)
Pages (from-to)966-969
Number of pages4
JournalArtificial Organs
Volume23
Issue number11
DOIs
StatePublished - Nov 1 1999
Externally publishedYes

Keywords

  • Cardiogenic shock
  • Extracorporeal life support
  • Extracorporeal membrane oxygenation

ASJC Scopus subject areas

  • Biophysics

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