Pathogenesis of HIV-associated cardiovascular complications

Giuseppe Barbaro, Stacy D. Fisher, Steven E. Lipshultz

Research output: Contribution to journalReview articlepeer-review

105 Scopus citations

Abstract

Reviews and studies published before the introduction of highly active antiretroviral therapy (HAART) have tracked the incidence and course of HIV infection in relation to cardiac illness in both children andadults. The introduction of HAART regimens has significantly modified the course of HIV disease, with longer survival rates and improvement of life quality in HIV-infected people expected. However, early data raised concerns about HAART being associatedwith an increase in both peripheral and coronary arterial diseases. In this review we discuss HIV-associated cardiovascular complications focusingon pathogenetic mechanisms that could have a rolein diagnosis, management, and therapy of these complications in the HAART era.

Original languageEnglish (US)
Pages (from-to)115-124
Number of pages10
JournalLancet Infectious Diseases
Volume1
Issue number2
DOIs
StatePublished - Sep 1 2001

ASJC Scopus subject areas

  • Infectious Diseases

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