TY - JOUR
T1 - Pathogenesis, Clinical Signs and Treatment Recommendations in Brittle Nails
T2 - A Review
AU - Chessa, Marco A.
AU - Iorizzo, Matilde
AU - Richert, Bertrand
AU - López-Estebaranz, Jose L.
AU - Rigopoulos, Dimitrios
AU - Tosti, Antonella
AU - Gupta, Aditya K.
AU - Di Chiacchio, Nilton
AU - Di Chiacchio, Nilton G.
AU - Rubin, Adam I.
AU - Baran, Robert
AU - Lipner, Shari R.
AU - Daniel, Ralph
AU - Chiheb, Soumya
AU - Grover, Chander
AU - Starace, Michela
AU - Piraccini, Bianca M.
N1 - Publisher Copyright:
© 2019, The Author(s).
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/2/1
Y1 - 2020/2/1
N2 - Nail plate brittleness (or fragility) is a common complaint affecting up to 20% of the population, especially women over 50 years of age, with fingernail fragility being more prevalent than toenail fragility. Nail brittleness is characterized by nails that split, flake and crumble, become soft and lose elasticity. The main clinical presentations are: onychoschizia, onychorrhexis, superficial granulation of keratin and worn-down nails. According to causative factors, we can distinguish 2 forms of nail fragility (NF): a primary “idiopathic or brittle nail syndrome” form and NF secondary to different causes such as inflammatory nail disorders, infections, systemic diseases and general conditions, traumas and alteration of the nail hydration. Optimal management requires treatment of the primary cause of brittle nails, when possible. In idiopathic NF oral supplementation, vitamins (especially biotin, also known as vitamin B7), trace elements and amino acids (especially cysteine) have been reported to be useful. In addition, several products, such as topical moisturizers and lacquers could be considered to restructure the affected nail plate and to reduce psychological impacts of this common problem.
AB - Nail plate brittleness (or fragility) is a common complaint affecting up to 20% of the population, especially women over 50 years of age, with fingernail fragility being more prevalent than toenail fragility. Nail brittleness is characterized by nails that split, flake and crumble, become soft and lose elasticity. The main clinical presentations are: onychoschizia, onychorrhexis, superficial granulation of keratin and worn-down nails. According to causative factors, we can distinguish 2 forms of nail fragility (NF): a primary “idiopathic or brittle nail syndrome” form and NF secondary to different causes such as inflammatory nail disorders, infections, systemic diseases and general conditions, traumas and alteration of the nail hydration. Optimal management requires treatment of the primary cause of brittle nails, when possible. In idiopathic NF oral supplementation, vitamins (especially biotin, also known as vitamin B7), trace elements and amino acids (especially cysteine) have been reported to be useful. In addition, several products, such as topical moisturizers and lacquers could be considered to restructure the affected nail plate and to reduce psychological impacts of this common problem.
KW - Aging
KW - Nail brittleness
KW - Nail cosmetic
KW - Nail fragility
KW - Onychorrhexis
KW - Onychoschizia
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U2 - 10.1007/s13555-019-00338-x
DO - 10.1007/s13555-019-00338-x
M3 - Review article
AN - SCOPUS:85075334453
VL - 10
SP - 15
EP - 27
JO - Dermatology and Therapy
JF - Dermatology and Therapy
SN - 2190-9172
IS - 1
ER -