Passive and active avoidance responses at two levels of shock after administration of melanocyte-stimulating hormone

Ransom Nockton, Abba J. Kastin, S. Thomas Elder, Andrew V. Schally

Research output: Contribution to journalArticle

10 Scopus citations


Rats receiving either melanocyte-stimulating hormone (MSH) or control solution were tested in a combined active and passive avoidance task involving different visual cues and two levels of shock. The group tested at 0.8 mA had a higher (P < 0.05) index of discrimination than the rats tested at the barely perceptible 0.4 mA. In this complex task, no effect of MSH was noted on behavior during acquisition or extinction, nor was there an effect upon adrenal or body weight. The lack of an observable action of MSH on activity as tested in the shuttle box, general activity meter, and open-field maze suggests that the previously reported influence of MSH on behavior cannot be adequately explained as a simple effect upon activity.

Original languageEnglish (US)
Pages (from-to)339-344
Number of pages6
JournalHormones and Behavior
Issue number4
StatePublished - Dec 1972


ASJC Scopus subject areas

  • Endocrinology
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience

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