Partial bladder transplantation with en bloc kidney transplant - The first case report of a 'bladder patch technique' in a human

T. Kato, G. Selvaggi, G. Burke, G. Ciancio, G. Zilleruelo, M. Hattori, R. Gosalbez, A. Tzakis

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Transplantation of the urinary bladder has not been reported in humans. We transplanted a portion of the donor bladder with an en bloc kidney graft in a 12-month-old girl. The child had a congenital hypoplastic single kidney with an ectopic ureteral opening into the vagina. Her native bladder was extremely small. Bilateral kidneys were transplanted en bloc with their ureters connected to a patch of the donor bladder, which encompassed the bilateral ureterovesical junctions (UVJs) (bladder patch technique). Approximately one-third of the donor bladder wall was used. The bladder patch reperfused well via blood supply from the ureters. Posttransplant cystoscopy with retrograde cystogram revealed a viable transplanted bladder with normal emptying of transplanted ureters. No reflux across the donor UVJs was seen in a voiding cystourethrogram. The child is doing well with normal renal function at 18-month follow-up.

Original languageEnglish (US)
Pages (from-to)1060-1063
Number of pages4
JournalAmerican Journal of Transplantation
Volume8
Issue number5
DOIs
StatePublished - May 1 2008

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Keywords

  • Bladder augmentation
  • En bloc transplant
  • Kidney transplantation
  • Pediatric renal transplantation

ASJC Scopus subject areas

  • Immunology

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