Paraneoplastic eosinophilic fasciitis: A case report

Sharon E. Jacob, Rashmi Lodha, Jonathan J. Cohen, Paolo Romanelli, Robert S. Kirsner

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


A 60-year-old white woman with polycythemia rubra vera post splenectomy in November 2001 was found to have peripheral white blood cell counts increasing over 3 months. Cytogenetics revealed trisomy of chromosomes 8 and 9, and bone marrow biopsy showed hypercellular, fibrotic bone marrow consistent with myelofibrosis of polycythemia rubra vera. Two months later, the patient developed acute swelling and pain in her lower extremities. The clinical symptoms along with confirmatory histology supported the diagnosis of eosinophilic fasciitis. This is the first reported case in the English literature of an association between polycythemia vera and eosinophilic fasciitis.

Original languageEnglish (US)
Pages (from-to)262-264
Number of pages3
JournalRheumatology International
Issue number5
StatePublished - Sep 2003


  • Eosinophilic fasciitis
  • Hematologic disorder
  • Paraneoplastic syndrome
  • Polycythemia rubra vera

ASJC Scopus subject areas

  • Rheumatology


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