Paradigm Shift in Utilization of Livers from Hepatitis C–Viremic Donors into Hepatitis C Virus–Negative Patients

Research output: Contribution to journalReview articlepeer-review

Abstract

Despite record-breaking numbers of liver transplants (LTs) performed in the United States in each of the last 7 years, many patients remain on the wait list as the demand for LT continues to exceed the supply of available donors. The emergence of highly effective and well-tolerated direct-acting antiviral therapy has transformed the clinical course and management of hepatitis C virus (HCV) in both the pretransplant and posttransplant setting. Historically, donor livers infected with HCV were either transplanted into patients already infected with HCV or discarded.

Original languageEnglish (US)
Pages (from-to)195-207
Number of pages13
JournalClinics in liver disease
Volume25
Issue number1
DOIs
StatePublished - Feb 2021

Keywords

  • HCV-positive donor
  • HCV-viremic donor
  • Hepatitis C virus
  • Liver transplantation

ASJC Scopus subject areas

  • Hepatology

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