TY - JOUR
T1 - Papillary muscle necrosis in a neonatal autopsy population
T2 - Incidence and associated clinical manifestations
AU - Behrman, Richard E.
AU - Setzer, Emmalee
AU - Ermocilla, Rufino
AU - Tonkin, Ina
AU - John, Elizabeth
AU - Sansa, Mara
AU - Cassady, George
PY - 1980/2
Y1 - 1980/2
N2 - Papillary muscle necrosis was found in 24 of 84 neonates without congenital heart disease who died and were autopsied during a 17-month study period. The lesion was most prevalent in infants ≥3,000 gm birth weight (59%), but papillary muscle necrosis was also noted in 25% of the infants of medium birth weight (1,500 to 2,999 gm) and in 19% of the very low-birth-weight infants (<1,500 gm). Papillary muscle necrosis in the highest birth-weight group correlated with five-minute Apgar scores of 6 or less, meconium aspiration syndrome, seizures, congestive heart failure, increased cardiothoracic ratio (≥0.60), and ischemic changes on electrocardiogram. In the medium- and very low-birth-weight groups, however, patients with papillary muscle necrosis could seldom be differentiated clinically from their birth-weight peers without the lesion, even in retrospect.
AB - Papillary muscle necrosis was found in 24 of 84 neonates without congenital heart disease who died and were autopsied during a 17-month study period. The lesion was most prevalent in infants ≥3,000 gm birth weight (59%), but papillary muscle necrosis was also noted in 25% of the infants of medium birth weight (1,500 to 2,999 gm) and in 19% of the very low-birth-weight infants (<1,500 gm). Papillary muscle necrosis in the highest birth-weight group correlated with five-minute Apgar scores of 6 or less, meconium aspiration syndrome, seizures, congestive heart failure, increased cardiothoracic ratio (≥0.60), and ischemic changes on electrocardiogram. In the medium- and very low-birth-weight groups, however, patients with papillary muscle necrosis could seldom be differentiated clinically from their birth-weight peers without the lesion, even in retrospect.
UR - http://www.scopus.com/inward/record.url?scp=0018835376&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018835376&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(80)80832-8
DO - 10.1016/S0022-3476(80)80832-8
M3 - Article
C2 - 7188702
AN - SCOPUS:0018835376
VL - 96
SP - 289
EP - 294
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 2
ER -