Papillary muscle necrosis in a neonatal autopsy population: Incidence and associated clinical manifestations

Richard E. Behrman, Emmalee S Bandstra, Rufino Ermocilla, Ina Tonkin, Elizabeth John, Mara Sansa, George Cassady

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Papillary muscle necrosis was found in 24 of 84 neonates without congenital heart disease who died and were autopsied during a 17-month study period. The lesion was most prevalent in infants ≥3,000 gm birth weight (59%), but papillary muscle necrosis was also noted in 25% of the infants of medium birth weight (1,500 to 2,999 gm) and in 19% of the very low-birth-weight infants (<1,500 gm). Papillary muscle necrosis in the highest birth-weight group correlated with five-minute Apgar scores of 6 or less, meconium aspiration syndrome, seizures, congestive heart failure, increased cardiothoracic ratio (≥0.60), and ischemic changes on electrocardiogram. In the medium- and very low-birth-weight groups, however, patients with papillary muscle necrosis could seldom be differentiated clinically from their birth-weight peers without the lesion, even in retrospect.

Original languageEnglish (US)
Pages (from-to)289-294
Number of pages6
JournalThe Journal of pediatrics
Volume96
Issue number2
DOIs
StatePublished - Jan 1 1980
Externally publishedYes

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Papillary Muscles
Birth Weight
Autopsy
Necrosis
Very Low Birth Weight Infant
Incidence
Population
Meconium Aspiration Syndrome
Apgar Score
Heart Diseases
Electrocardiography
Seizures
Heart Failure
Newborn Infant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Papillary muscle necrosis in a neonatal autopsy population : Incidence and associated clinical manifestations. / Behrman, Richard E.; Bandstra, Emmalee S; Ermocilla, Rufino; Tonkin, Ina; John, Elizabeth; Sansa, Mara; Cassady, George.

In: The Journal of pediatrics, Vol. 96, No. 2, 01.01.1980, p. 289-294.

Research output: Contribution to journalArticle

Behrman, Richard E. ; Bandstra, Emmalee S ; Ermocilla, Rufino ; Tonkin, Ina ; John, Elizabeth ; Sansa, Mara ; Cassady, George. / Papillary muscle necrosis in a neonatal autopsy population : Incidence and associated clinical manifestations. In: The Journal of pediatrics. 1980 ; Vol. 96, No. 2. pp. 289-294.
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