Papillary muscle necrosis in a neonatal autopsy population: Incidence and associated clinical manifestations

Richard E. Behrman, Emmalee Setzer, Rufino Ermocilla, Ina Tonkin, Elizabeth John, Mara Sansa, George Cassady

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

Papillary muscle necrosis was found in 24 of 84 neonates without congenital heart disease who died and were autopsied during a 17-month study period. The lesion was most prevalent in infants ≥3,000 gm birth weight (59%), but papillary muscle necrosis was also noted in 25% of the infants of medium birth weight (1,500 to 2,999 gm) and in 19% of the very low-birth-weight infants (<1,500 gm). Papillary muscle necrosis in the highest birth-weight group correlated with five-minute Apgar scores of 6 or less, meconium aspiration syndrome, seizures, congestive heart failure, increased cardiothoracic ratio (≥0.60), and ischemic changes on electrocardiogram. In the medium- and very low-birth-weight groups, however, patients with papillary muscle necrosis could seldom be differentiated clinically from their birth-weight peers without the lesion, even in retrospect.

Original languageEnglish (US)
Pages (from-to)289-294
Number of pages6
JournalThe Journal of Pediatrics
Volume96
Issue number2
DOIs
StatePublished - Feb 1980
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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