Pancreatic tissues

Grace J. Lim, Anthony Atala

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Diabetes mellitus, a disorder of glucose homeostasis, is a leading cause of morbidity and premature mortality in the world. During the last 75 years, since the discovery of insulin therapy, there have been no new major developments in treating this disease. Thus, the ability to engineer pancreatic tissue is an attractive approach, and as tissue engineering technology advances, this novel therapy is now becoming a reality. Transplantation of engineered pancreatic islets will not only eliminate the need for daily insulin injections, but will also prove effective in preventing or retarding the development of complications associated with diabetes. In this chapter, current technologies for pancreatic tissue engineering, novel sources for insulin producing b-cells, and safe transplantation techniques to treat diabetes are discussed.

Original languageEnglish
Title of host publicationTissue Engineering: From Lab to Clinic
PublisherSpringer-Verlag Berlin Heidelberg
Pages521-536
Number of pages16
ISBN (Print)9783642028243, 9783642028236
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

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Medical problems
Insulin
Tissue Engineering
Tissue
Tissue engineering
Technology
Islets of Langerhans Transplantation
Premature Mortality
Engineering technology
Cell Transplantation
Diabetes Mellitus
Homeostasis
Morbidity
Engineers
Glucose
Injections
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Lim, G. J., & Atala, A. (2011). Pancreatic tissues. In Tissue Engineering: From Lab to Clinic (pp. 521-536). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-02824-3_24

Pancreatic tissues. / Lim, Grace J.; Atala, Anthony.

Tissue Engineering: From Lab to Clinic. Springer-Verlag Berlin Heidelberg, 2011. p. 521-536.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lim, GJ & Atala, A 2011, Pancreatic tissues. in Tissue Engineering: From Lab to Clinic. Springer-Verlag Berlin Heidelberg, pp. 521-536. https://doi.org/10.1007/978-3-642-02824-3_24
Lim GJ, Atala A. Pancreatic tissues. In Tissue Engineering: From Lab to Clinic. Springer-Verlag Berlin Heidelberg. 2011. p. 521-536 https://doi.org/10.1007/978-3-642-02824-3_24
Lim, Grace J. ; Atala, Anthony. / Pancreatic tissues. Tissue Engineering: From Lab to Clinic. Springer-Verlag Berlin Heidelberg, 2011. pp. 521-536
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