Pancreatic Cysts

Jodie A. Barkin, Jamie S Barkin

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Pancreatic cysts are commonly found on cross-sectional imaging. The question arises in determining which lesions are premalignant or malignant and may require further testing, intervention, or follow-up. In pancreatic cysts without obvious malignancy on imaging, we approach them using the Four "S" Criteria. These are (1) symptoms that may be originating from the pancreatic cyst; (2) size of the cyst 2 cm or larger and/or main pancreatic duct greater than 5 mm; (3) survival of the patient, based on comorbidity index to determine surgical fitness; and then endoscopic ultrasound with fine needle aspiration (FNA) recommended to determine (4) solid component presence in the cyst, namely, nodule or thick walls, as well as to perform FNA to obtain cyst content. Current cyst fluid analysis options include use of cytology to determine presence of malignancy and carcinoembryonic antigen and fluid genetics to identify potentially premalignant lesions. The aims of this article are to explore current management guidelines for pancreatic cysts, present a comprehensive approach to pancreatic cysts, and explain the advantages and disadvantages of each option for evaluation of pancreatic cysts including endoscopic ultrasound with FNAwith cyst fluid analysis using an evidence-based approach.

Original languageEnglish (US)
Pages (from-to)735-741
Number of pages7
JournalPancreas
Volume46
Issue number6
DOIs
StatePublished - 2017

Fingerprint

Pancreatic Cyst
Cyst Fluid
Cysts
Fine Needle Biopsy
Pancreatic Ducts
Carcinoembryonic Antigen
Cell Biology
Comorbidity
Neoplasms
Guidelines
Survival

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Pancreatic Cysts. / Barkin, Jodie A.; Barkin, Jamie S.

In: Pancreas, Vol. 46, No. 6, 2017, p. 735-741.

Research output: Contribution to journalReview article

Barkin, Jodie A. ; Barkin, Jamie S. / Pancreatic Cysts. In: Pancreas. 2017 ; Vol. 46, No. 6. pp. 735-741.
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