Abstract
This chapter discusses palliative radiotherapy for malignant neuropathic pain, adrenal, choroidal, and skin metastases. There are very little data in the literature on the use of RT for malignant neuropathic pain. One randomized trial on neuropathic pain due to bone metastases showed similar response rates to those observed for localized bone pain but leaves the question of optimal fractionation open. Both external beam radiation therapy (EBRT) and stereotactic body radiation therapy (SBRT) are effective for palliation of painful adrenal metastases, with response rates of about 85%, although the latter technique is primarily used for local control and disease-free survival benefit. EBRT has been used to treat symptomatic cutaneous metastases from a wide variety of carcinomas and for recurrent/metastatic primary skin malignancies including cutaneous malignant melanoma (CMM), Merkel cell carcinoma (MCC), and primary cutaneous lymphoma (PCL).
| Original language | English |
|---|---|
| Title of host publication | Radiation Oncology in Palliative Cancer Care |
| Publisher | John Wiley and Sons |
| Pages | 299-316 |
| Number of pages | 18 |
| ISBN (Print) | 9781118484159 |
| DOIs | |
| State | Published - Mar 7 2013 |
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Keywords
- Adrenal metastases
- Choroidal metastases
- External beam radiation therapy (EBRT)
- Malignant neuropathic pain
- Palliative radiotherapy
- Skin metastases
- Stereotactic body radiation therapy (SBRT)
ASJC Scopus subject areas
- Medicine(all)
Cite this
Palliative Radiotherapy for Malignant Neuropathic Pain, Adrenal, Choroidal, and Skin Metastases. / Roos, Daniel E.; Wolfson, Aaron.
Radiation Oncology in Palliative Cancer Care. John Wiley and Sons, 2013. p. 299-316.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Palliative Radiotherapy for Malignant Neuropathic Pain, Adrenal, Choroidal, and Skin Metastases
AU - Roos, Daniel E.
AU - Wolfson, Aaron
PY - 2013/3/7
Y1 - 2013/3/7
N2 - This chapter discusses palliative radiotherapy for malignant neuropathic pain, adrenal, choroidal, and skin metastases. There are very little data in the literature on the use of RT for malignant neuropathic pain. One randomized trial on neuropathic pain due to bone metastases showed similar response rates to those observed for localized bone pain but leaves the question of optimal fractionation open. Both external beam radiation therapy (EBRT) and stereotactic body radiation therapy (SBRT) are effective for palliation of painful adrenal metastases, with response rates of about 85%, although the latter technique is primarily used for local control and disease-free survival benefit. EBRT has been used to treat symptomatic cutaneous metastases from a wide variety of carcinomas and for recurrent/metastatic primary skin malignancies including cutaneous malignant melanoma (CMM), Merkel cell carcinoma (MCC), and primary cutaneous lymphoma (PCL).
AB - This chapter discusses palliative radiotherapy for malignant neuropathic pain, adrenal, choroidal, and skin metastases. There are very little data in the literature on the use of RT for malignant neuropathic pain. One randomized trial on neuropathic pain due to bone metastases showed similar response rates to those observed for localized bone pain but leaves the question of optimal fractionation open. Both external beam radiation therapy (EBRT) and stereotactic body radiation therapy (SBRT) are effective for palliation of painful adrenal metastases, with response rates of about 85%, although the latter technique is primarily used for local control and disease-free survival benefit. EBRT has been used to treat symptomatic cutaneous metastases from a wide variety of carcinomas and for recurrent/metastatic primary skin malignancies including cutaneous malignant melanoma (CMM), Merkel cell carcinoma (MCC), and primary cutaneous lymphoma (PCL).
KW - Adrenal metastases
KW - Choroidal metastases
KW - External beam radiation therapy (EBRT)
KW - Malignant neuropathic pain
KW - Palliative radiotherapy
KW - Skin metastases
KW - Stereotactic body radiation therapy (SBRT)
UR - http://www.scopus.com/inward/record.url?scp=84886329109&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886329109&partnerID=8YFLogxK
U2 - 10.1002/9781118607152.ch24
DO - 10.1002/9781118607152.ch24
M3 - Chapter
AN - SCOPUS:84886329109
SN - 9781118484159
SP - 299
EP - 316
BT - Radiation Oncology in Palliative Cancer Care
PB - John Wiley and Sons
ER -