'Painting' the target: How local molecular cues define synaptic relationships

Akira Chiba, Demian Rose

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A majority of studies on neuronal growth cones focus on the features that particular groups of neurons share. In contrast, questions such as how specific growth cones respond very differently to the same extrinsic cues require cell-specific experimentation. The most succinct cell-specific growth cone responses occur during synaptic targeting. Recent studies have examined one specific growth cone, the Drosophila RP3 motoneuron growth cone, in variously altered microenvironments. In this review, we summarize how such studies are beginning to uncover the repertoire of extrinsic cues that influence the synaptic targeting of a single growth cone.

Original languageEnglish
Pages (from-to)941-948
Number of pages8
JournalBioEssays
Volume20
Issue number11
DOIs
StatePublished - Nov 1 1998
Externally publishedYes

Fingerprint

Growth Cones
Paintings
cones (retina)
Painting
Cues
Cones
Motor Neurons
motor neurons
Drosophila
Neurons
neurons
cells

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Biochemistry
  • Cell Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Agricultural and Biological Sciences (miscellaneous)
  • Plant Science

Cite this

'Painting' the target : How local molecular cues define synaptic relationships. / Chiba, Akira; Rose, Demian.

In: BioEssays, Vol. 20, No. 11, 01.11.1998, p. 941-948.

Research output: Contribution to journalArticle

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