Paget's Disease of Bone in Patients Younger Than 40 Years

Theodore J. Choma, Timothy R. Kuklo, Richard B. Islinger, Mark D. Murphey, H. Thomas Temple

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Paget's disease of bone, although common in the United States, is relatively rare in patients younger than 40 years. In a large archival series, 10% of patients with Paget's disease of bone were younger than 40 years. Pain followed by pathologic fracture was the most common presenting complaint in this group of patients. There was no gender difference comparing the younger group with the older group of patients. Of the 521 patients in this series, only 10 were African-American; the others were Caucasians. Seven African-American patients were in the group of patients who were younger than 40 years. Appendicular and monostotic bone involvement was more frequent in the younger age group although these differences were not statistically significant. The incidence of malignant transformation in pagetic bone was high (30.3%), and is a reflection of the high volume of uncommon tumor referrals to our consultation service. However, there were no cases of associated malignancies in the group of patients younger than 40 years.

Original languageEnglish (US)
Pages (from-to)202-204
Number of pages3
JournalClinical orthopaedics and related research
Issue number418
DOIs
StatePublished - Jan 2004

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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    Choma, T. J., Kuklo, T. R., Islinger, R. B., Murphey, M. D., & Temple, H. T. (2004). Paget's Disease of Bone in Patients Younger Than 40 Years. Clinical orthopaedics and related research, (418), 202-204. https://doi.org/10.1097/00003086-200401000-00033