From 1994 to 1997, four patients, 2 males and 2 females, ranging in age from 13 to 50 years, were referred to our Department because of dystrophic lesions in twenty nails, palmar and plantar hyperkeratosis, leukokeratosis of the tongue and mucous membranes and follicular hyperkeratosis. Detailed questioning of the patients revealed that, in all of them, lesions appeared at birth or in early childhood and nail disease arised symmetrically and before the other anomalies. Patient's history as well as the clinical and histological features suggested the diagnosis of pachyonychia congenita syndrome (PCS).
|Number of pages||4|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|State||Published - Jan 1 1999|
- Lewandowsky syndrome
- Nail diseases congenital
- Pachyonychia congenita
ASJC Scopus subject areas