Oxygen exchange and vascular resistance in the totally perfused rainbow trout.

C. M. Wood, B. R. McMahon, D. G. McDonald

Research output: Contribution to journalArticle

Abstract

A whole trout preparation (Salmo gairdneri) externally ventilated with water and internally perfused with artificial medium via a cardiac pump is discribed for the study of O2 exchange and vascular resistance. As cardiac output (Q) was raised, ventral and dorsal aortic pressures increased while branchial (Rg) and systemic (Rs) vascular resistances fell, reflecting considerable passive distensibility. Arterial oxygenation was negative at low Qs due to significant internal O2 demand by the gill tissue, but increased to zero or positive values at intermediate Qs, and eventually declined at high Qs because of transit time limitation. O2 uptake from the ventilatory flow rose with increasing Q. Epinephrine (10(-5) M) decreased Rg, increased Rs, and enhanced arterial oxygenation. Artificial elevation of dorsal aortic pressure decreased Rg but did not affect arterial oxygenation. A 10-fold elevation of ventilatory flow increased arterial oxygenation but did not alter Rg or Rs. Endogenous metabolism of branchial tissue accounted for 11.7% of resting O2 uptake in vivo, and comprised an internal component taking O2 from perfusion flow and an external component drawing O2 from ventilatory flow.

Original languageEnglish
JournalThe American journal of physiology
Volume234
Issue number5
StatePublished - May 1 1978

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Oncorhynchus mykiss
Vascular Resistance
Arterial Pressure
Oxygen
Trout
Cardiac Output
Epinephrine
Perfusion
Water

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Oxygen exchange and vascular resistance in the totally perfused rainbow trout. / Wood, C. M.; McMahon, B. R.; McDonald, D. G.

In: The American journal of physiology, Vol. 234, No. 5, 01.05.1978.

Research output: Contribution to journalArticle

Wood, C. M. ; McMahon, B. R. ; McDonald, D. G. / Oxygen exchange and vascular resistance in the totally perfused rainbow trout. In: The American journal of physiology. 1978 ; Vol. 234, No. 5.
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