MIF was demonstrated to antagonize the central and peripheral effects of oxotremorine in normal as well as in hypophysectomized mice. Its effectiveness in hypophysectomized mice confirms our earlier report that MIF exerts actions upon the CNS which are independent of its MSH release-inhibiting activity.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Jul 1972|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)