Over-the-counter topical antimicrobials

Effective treatments?

Stephen C Davis, Alejandro L. Cazzaniga, William H. Eaglstein, Patricia M. Mertz

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

There are many over-the-counter (OTC) bandage products available. In addition to their direct purchase by the public, many physicians provide OTC bandages to their patents after minor surgeries. The aim of this study was to evaluate in a well established porcine model the efficacy against Staphylococcus aureus of four OTC antimicrobial containing bandages as compared to two OTC ointments. Multiple partial thickness wounds were made on the backs of four pigs. The wounds were treated within 20 min after S. aureus inoculation. The wounds were cultured quantitatively at 24 and 48 h. Only one of the antibiotic bandages and one of the topical ointments were effective in reducing S. aureus proliferation in partial thickness wounds. The two treatments that were effective were the only treatments that contained neomycin. Although many OTC bandages and ointments contain antimicrobials, they may not be effective at reducing bacteria in wounds.

Original languageEnglish
Pages (from-to)190-195
Number of pages6
JournalArchives of Dermatological Research
Volume297
Issue number5
DOIs
StatePublished - Nov 1 2005

Fingerprint

Bandages
Ointments
Wounds and Injuries
Staphylococcus aureus
Swine
Therapeutics
Minor Surgical Procedures
Neomycin
Patents
Anti-Bacterial Agents
Bacteria
Physicians

Keywords

  • Antimicrobials
  • Bacteria
  • Staphylococcus aureus
  • Wounds

ASJC Scopus subject areas

  • Dermatology

Cite this

Over-the-counter topical antimicrobials : Effective treatments? / Davis, Stephen C; Cazzaniga, Alejandro L.; Eaglstein, William H.; Mertz, Patricia M.

In: Archives of Dermatological Research, Vol. 297, No. 5, 01.11.2005, p. 190-195.

Research output: Contribution to journalArticle

Davis, Stephen C ; Cazzaniga, Alejandro L. ; Eaglstein, William H. ; Mertz, Patricia M. / Over-the-counter topical antimicrobials : Effective treatments?. In: Archives of Dermatological Research. 2005 ; Vol. 297, No. 5. pp. 190-195.
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