Outer Retina Ischemic Infarction—A Newly Recognized Complication of Cataract Extraction and Closed Vitrectomy: Part 2. An Animal Model

Richard Parrish, J. Donald M. Gass, Douglas R. Anderson

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Intraocular pressure was artificially elevated above systolic blood pressure in 40 owl monkey eyes. Diffuse retinal whitening of the posterior pole and subsequent retinal pigment epithelial disruption were produced in nine of ten eyes with high pressure for 90 minutes or longer, but also in a few eyes with high pressure for a shorter duration. Fluorescein angiography and histologic examination demonstrated damage of the photoreceptors and retinal pigment epithelium with sparing of the inner retinal layers. This animal model duplicates the acute visual loss due to outer retinal infarction that sometimes occurs after closed vitrectomy or after continuous external ocular compression in preparation for surgery.

Original languageEnglish (US)
Pages (from-to)1472-1477
Number of pages6
JournalOphthalmology
Volume89
Issue number12
DOIs
StatePublished - Jan 1 1982

Keywords

  • cataract extraction
  • choroidal infarction
  • intraocular pressure
  • retinal ischemia
  • surgical complication
  • vitrectomy

ASJC Scopus subject areas

  • Ophthalmology

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