Outcomes after severe distal tibia, ankle, and/or foot trauma

Comparison of limb salvage versus transtibial amputation (OUTLET)

Michael J. Bosse, David Teague, Lisa Reider, Joshua L. Gary, Saam Morshed, Rachel B. Seymour, James Toledano, Lisa K. Cannada, Barbara Steverson, Daniel O. Scharfstein, Jason Luly, Ellen J. MacKenzie, W. M. Ricci, C. M. McAndrew, A. N. Miller, M. J. Gardner, A. Spraggs-Hughes, C. Churchill, J. R. Hsu, S. H. Sims & 87 others M. A. Karunakar, D. J. Hak, C. Mauffrey, P. F. Stahel, H. J. Gissel, C. E. Henderson, R. M. Reilly, R. D. Zura, M. Manson, J. O. Anglen, B. H. Mullis, H. R. Mir, A. H. Schmidt, G. E. Mirick, J. R. Westberg, S. R. Konda, A. T. Sorkin, K. D. Shively, G. E. Gaski, J. P. Ertl, L. C. Hill, H. A. Vallier, M. A. Breslin, J. Langford, P. J. Harriott, K. M. Kuhn, D. C. Gregory, D. L. Sietsema, C. B. Jones, A. H. Horne, R. A. Hayda, C. T. Born, M. J. Crisco, D. J. Stinner, P. M. Osborn, M. Norton, J. M. Wilken, J. T. Watson, S. A. Dawson, W. C. McGarvey, A. Choo, J. W. Munz, M. C. Galpin, T. Miclau, T. Belaye, M. Willey, T. Manson, C. T. LeBrun, R. V. O'Toole, A. L. Howe, J. W. Nascone, Y. Degani, M. F. Sciadini, James Hutson, Jr., G. M. Zych, P. F. Bergin, M. L. Graves, G. V. Russell, C. A. Spitler, J. Hydrick, W. J. Ertl, Z. V. Roberts, I. S. Tarkin, D. B. Weiss, V. LesterBallard, R. Firoozabadi, J. Agel, W. T. Obremskey, A. Rodriguez-Buitrago, A. A. Jahangir, M. K. Sethi, V. Gajari, E. J. Burgos, R. R. Tummuru, K. R. Archer, E. A. Carroll, J. B. Goodman, J. J. Halvorson, M. B. Holden, W. T. Gordon, X. Ceniceros, S. L. Waggoner, L. E. Allen, A. R. Carlini, R. C. Castillo, R. Kirk, Stephen Quinnan

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Severe foot and ankle injuries are complex and challenging to treat, often requiring multiple operations to salvage the limb contributing to a prolonged healing period. There is some evidence to suggest that early amputation for some patients may result in better long-term outcomes than limb salvage. The challenge is to identify the regional injury burden for an individual that would suggest a better outcome with an amputation. The OUTLET study is a prospective, multicenter observational study comparing 18-month outcomes after limb salvage versus early amputation among patients aged 18-60 years with severe distal tibia, ankle, and foot injuries. This study aims to build upon the previous work of the Lower Extremity Assessment Project by identifying the injury and patient characteristics that help define a subgroup of salvage patients who will have better outcomes had they undergone a transtibial amputation.

Original languageEnglish (US)
Pages (from-to)S48-S55
JournalJournal of orthopaedic trauma
Volume31
DOIs
StatePublished - Jan 1 2017

Fingerprint

Limb Salvage
Tibia
Amputation
Ankle
Foot
Foot Injuries
Ankle Injuries
Wounds and Injuries
Multicenter Studies
Observational Studies
Lower Extremity

Keywords

  • Amputation
  • Limb salvage
  • Severe foot and ankle injuries

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Outcomes after severe distal tibia, ankle, and/or foot trauma : Comparison of limb salvage versus transtibial amputation (OUTLET). / Bosse, Michael J.; Teague, David; Reider, Lisa; Gary, Joshua L.; Morshed, Saam; Seymour, Rachel B.; Toledano, James; Cannada, Lisa K.; Steverson, Barbara; Scharfstein, Daniel O.; Luly, Jason; MacKenzie, Ellen J.; Ricci, W. M.; McAndrew, C. M.; Miller, A. N.; Gardner, M. J.; Spraggs-Hughes, A.; Churchill, C.; Hsu, J. R.; Sims, S. H.; Karunakar, M. A.; Hak, D. J.; Mauffrey, C.; Stahel, P. F.; Gissel, H. J.; Henderson, C. E.; Reilly, R. M.; Zura, R. D.; Manson, M.; Anglen, J. O.; Mullis, B. H.; Mir, H. R.; Schmidt, A. H.; Mirick, G. E.; Westberg, J. R.; Konda, S. R.; Sorkin, A. T.; Shively, K. D.; Gaski, G. E.; Ertl, J. P.; Hill, L. C.; Vallier, H. A.; Breslin, M. A.; Langford, J.; Harriott, P. J.; Kuhn, K. M.; Gregory, D. C.; Sietsema, D. L.; Jones, C. B.; Horne, A. H.; Hayda, R. A.; Born, C. T.; Crisco, M. J.; Stinner, D. J.; Osborn, P. M.; Norton, M.; Wilken, J. M.; Watson, J. T.; Dawson, S. A.; McGarvey, W. C.; Choo, A.; Munz, J. W.; Galpin, M. C.; Miclau, T.; Belaye, T.; Willey, M.; Manson, T.; LeBrun, C. T.; O'Toole, R. V.; Howe, A. L.; Nascone, J. W.; Degani, Y.; Sciadini, M. F.; Hutson, Jr., James; Zych, G. M.; Bergin, P. F.; Graves, M. L.; Russell, G. V.; Spitler, C. A.; Hydrick, J.; Ertl, W. J.; Roberts, Z. V.; Tarkin, I. S.; Weiss, D. B.; LesterBallard, V.; Firoozabadi, R.; Agel, J.; Obremskey, W. T.; Rodriguez-Buitrago, A.; Jahangir, A. A.; Sethi, M. K.; Gajari, V.; Burgos, E. J.; Tummuru, R. R.; Archer, K. R.; Carroll, E. A.; Goodman, J. B.; Halvorson, J. J.; Holden, M. B.; Gordon, W. T.; Ceniceros, X.; Waggoner, S. L.; Allen, L. E.; Carlini, A. R.; Castillo, R. C.; Kirk, R.; Quinnan, Stephen.

In: Journal of orthopaedic trauma, Vol. 31, 01.01.2017, p. S48-S55.

Research output: Contribution to journalArticle

Bosse, MJ, Teague, D, Reider, L, Gary, JL, Morshed, S, Seymour, RB, Toledano, J, Cannada, LK, Steverson, B, Scharfstein, DO, Luly, J, MacKenzie, EJ, Ricci, WM, McAndrew, CM, Miller, AN, Gardner, MJ, Spraggs-Hughes, A, Churchill, C, Hsu, JR, Sims, SH, Karunakar, MA, Hak, DJ, Mauffrey, C, Stahel, PF, Gissel, HJ, Henderson, CE, Reilly, RM, Zura, RD, Manson, M, Anglen, JO, Mullis, BH, Mir, HR, Schmidt, AH, Mirick, GE, Westberg, JR, Konda, SR, Sorkin, AT, Shively, KD, Gaski, GE, Ertl, JP, Hill, LC, Vallier, HA, Breslin, MA, Langford, J, Harriott, PJ, Kuhn, KM, Gregory, DC, Sietsema, DL, Jones, CB, Horne, AH, Hayda, RA, Born, CT, Crisco, MJ, Stinner, DJ, Osborn, PM, Norton, M, Wilken, JM, Watson, JT, Dawson, SA, McGarvey, WC, Choo, A, Munz, JW, Galpin, MC, Miclau, T, Belaye, T, Willey, M, Manson, T, LeBrun, CT, O'Toole, RV, Howe, AL, Nascone, JW, Degani, Y, Sciadini, MF, Hutson, Jr., J, Zych, GM, Bergin, PF, Graves, ML, Russell, GV, Spitler, CA, Hydrick, J, Ertl, WJ, Roberts, ZV, Tarkin, IS, Weiss, DB, LesterBallard, V, Firoozabadi, R, Agel, J, Obremskey, WT, Rodriguez-Buitrago, A, Jahangir, AA, Sethi, MK, Gajari, V, Burgos, EJ, Tummuru, RR, Archer, KR, Carroll, EA, Goodman, JB, Halvorson, JJ, Holden, MB, Gordon, WT, Ceniceros, X, Waggoner, SL, Allen, LE, Carlini, AR, Castillo, RC, Kirk, R & Quinnan, S 2017, 'Outcomes after severe distal tibia, ankle, and/or foot trauma: Comparison of limb salvage versus transtibial amputation (OUTLET)', Journal of orthopaedic trauma, vol. 31, pp. S48-S55. https://doi.org/10.1097/BOT.0000000000000799
Bosse, Michael J. ; Teague, David ; Reider, Lisa ; Gary, Joshua L. ; Morshed, Saam ; Seymour, Rachel B. ; Toledano, James ; Cannada, Lisa K. ; Steverson, Barbara ; Scharfstein, Daniel O. ; Luly, Jason ; MacKenzie, Ellen J. ; Ricci, W. M. ; McAndrew, C. M. ; Miller, A. N. ; Gardner, M. J. ; Spraggs-Hughes, A. ; Churchill, C. ; Hsu, J. R. ; Sims, S. H. ; Karunakar, M. A. ; Hak, D. J. ; Mauffrey, C. ; Stahel, P. F. ; Gissel, H. J. ; Henderson, C. E. ; Reilly, R. M. ; Zura, R. D. ; Manson, M. ; Anglen, J. O. ; Mullis, B. H. ; Mir, H. R. ; Schmidt, A. H. ; Mirick, G. E. ; Westberg, J. R. ; Konda, S. R. ; Sorkin, A. T. ; Shively, K. D. ; Gaski, G. E. ; Ertl, J. P. ; Hill, L. C. ; Vallier, H. A. ; Breslin, M. A. ; Langford, J. ; Harriott, P. J. ; Kuhn, K. M. ; Gregory, D. C. ; Sietsema, D. L. ; Jones, C. B. ; Horne, A. H. ; Hayda, R. A. ; Born, C. T. ; Crisco, M. J. ; Stinner, D. J. ; Osborn, P. M. ; Norton, M. ; Wilken, J. M. ; Watson, J. T. ; Dawson, S. A. ; McGarvey, W. C. ; Choo, A. ; Munz, J. W. ; Galpin, M. C. ; Miclau, T. ; Belaye, T. ; Willey, M. ; Manson, T. ; LeBrun, C. T. ; O'Toole, R. V. ; Howe, A. L. ; Nascone, J. W. ; Degani, Y. ; Sciadini, M. F. ; Hutson, Jr., James ; Zych, G. M. ; Bergin, P. F. ; Graves, M. L. ; Russell, G. V. ; Spitler, C. A. ; Hydrick, J. ; Ertl, W. J. ; Roberts, Z. V. ; Tarkin, I. S. ; Weiss, D. B. ; LesterBallard, V. ; Firoozabadi, R. ; Agel, J. ; Obremskey, W. T. ; Rodriguez-Buitrago, A. ; Jahangir, A. A. ; Sethi, M. K. ; Gajari, V. ; Burgos, E. J. ; Tummuru, R. R. ; Archer, K. R. ; Carroll, E. A. ; Goodman, J. B. ; Halvorson, J. J. ; Holden, M. B. ; Gordon, W. T. ; Ceniceros, X. ; Waggoner, S. L. ; Allen, L. E. ; Carlini, A. R. ; Castillo, R. C. ; Kirk, R. ; Quinnan, Stephen. / Outcomes after severe distal tibia, ankle, and/or foot trauma : Comparison of limb salvage versus transtibial amputation (OUTLET). In: Journal of orthopaedic trauma. 2017 ; Vol. 31. pp. S48-S55.
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TY - JOUR

T1 - Outcomes after severe distal tibia, ankle, and/or foot trauma

T2 - Comparison of limb salvage versus transtibial amputation (OUTLET)

AU - Bosse, Michael J.

AU - Teague, David

AU - Reider, Lisa

AU - Gary, Joshua L.

AU - Morshed, Saam

AU - Seymour, Rachel B.

AU - Toledano, James

AU - Cannada, Lisa K.

AU - Steverson, Barbara

AU - Scharfstein, Daniel O.

AU - Luly, Jason

AU - MacKenzie, Ellen J.

AU - Ricci, W. M.

AU - McAndrew, C. M.

AU - Miller, A. N.

AU - Gardner, M. J.

AU - Spraggs-Hughes, A.

AU - Churchill, C.

AU - Hsu, J. R.

AU - Sims, S. H.

AU - Karunakar, M. A.

AU - Hak, D. J.

AU - Mauffrey, C.

AU - Stahel, P. F.

AU - Gissel, H. J.

AU - Henderson, C. E.

AU - Reilly, R. M.

AU - Zura, R. D.

AU - Manson, M.

AU - Anglen, J. O.

AU - Mullis, B. H.

AU - Mir, H. R.

AU - Schmidt, A. H.

AU - Mirick, G. E.

AU - Westberg, J. R.

AU - Konda, S. R.

AU - Sorkin, A. T.

AU - Shively, K. D.

AU - Gaski, G. E.

AU - Ertl, J. P.

AU - Hill, L. C.

AU - Vallier, H. A.

AU - Breslin, M. A.

AU - Langford, J.

AU - Harriott, P. J.

AU - Kuhn, K. M.

AU - Gregory, D. C.

AU - Sietsema, D. L.

AU - Jones, C. B.

AU - Horne, A. H.

AU - Hayda, R. A.

AU - Born, C. T.

AU - Crisco, M. J.

AU - Stinner, D. J.

AU - Osborn, P. M.

AU - Norton, M.

AU - Wilken, J. M.

AU - Watson, J. T.

AU - Dawson, S. A.

AU - McGarvey, W. C.

AU - Choo, A.

AU - Munz, J. W.

AU - Galpin, M. C.

AU - Miclau, T.

AU - Belaye, T.

AU - Willey, M.

AU - Manson, T.

AU - LeBrun, C. T.

AU - O'Toole, R. V.

AU - Howe, A. L.

AU - Nascone, J. W.

AU - Degani, Y.

AU - Sciadini, M. F.

AU - Hutson, Jr., James

AU - Zych, G. M.

AU - Bergin, P. F.

AU - Graves, M. L.

AU - Russell, G. V.

AU - Spitler, C. A.

AU - Hydrick, J.

AU - Ertl, W. J.

AU - Roberts, Z. V.

AU - Tarkin, I. S.

AU - Weiss, D. B.

AU - LesterBallard, V.

AU - Firoozabadi, R.

AU - Agel, J.

AU - Obremskey, W. T.

AU - Rodriguez-Buitrago, A.

AU - Jahangir, A. A.

AU - Sethi, M. K.

AU - Gajari, V.

AU - Burgos, E. J.

AU - Tummuru, R. R.

AU - Archer, K. R.

AU - Carroll, E. A.

AU - Goodman, J. B.

AU - Halvorson, J. J.

AU - Holden, M. B.

AU - Gordon, W. T.

AU - Ceniceros, X.

AU - Waggoner, S. L.

AU - Allen, L. E.

AU - Carlini, A. R.

AU - Castillo, R. C.

AU - Kirk, R.

AU - Quinnan, Stephen

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Severe foot and ankle injuries are complex and challenging to treat, often requiring multiple operations to salvage the limb contributing to a prolonged healing period. There is some evidence to suggest that early amputation for some patients may result in better long-term outcomes than limb salvage. The challenge is to identify the regional injury burden for an individual that would suggest a better outcome with an amputation. The OUTLET study is a prospective, multicenter observational study comparing 18-month outcomes after limb salvage versus early amputation among patients aged 18-60 years with severe distal tibia, ankle, and foot injuries. This study aims to build upon the previous work of the Lower Extremity Assessment Project by identifying the injury and patient characteristics that help define a subgroup of salvage patients who will have better outcomes had they undergone a transtibial amputation.

AB - Severe foot and ankle injuries are complex and challenging to treat, often requiring multiple operations to salvage the limb contributing to a prolonged healing period. There is some evidence to suggest that early amputation for some patients may result in better long-term outcomes than limb salvage. The challenge is to identify the regional injury burden for an individual that would suggest a better outcome with an amputation. The OUTLET study is a prospective, multicenter observational study comparing 18-month outcomes after limb salvage versus early amputation among patients aged 18-60 years with severe distal tibia, ankle, and foot injuries. This study aims to build upon the previous work of the Lower Extremity Assessment Project by identifying the injury and patient characteristics that help define a subgroup of salvage patients who will have better outcomes had they undergone a transtibial amputation.

KW - Amputation

KW - Limb salvage

KW - Severe foot and ankle injuries

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DO - 10.1097/BOT.0000000000000799

M3 - Article

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SP - S48-S55

JO - Journal of Orthopaedic Trauma

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SN - 0890-5339

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