Outcome of Exfoliative Rejection After Isolated Intestinal Transplantation in an Adult: Case Report

T. Yandza, S. M. Schneider, S. Nishida, B. Goubaux, L. Badan, G. Vanbiervliet, M. C. Saint-Paul, G. Bernard, C. Laffont, M. Gari-Toussaint, F. Girard-Pipau, V. Miton, A. Rahili, G. Zeanandin, D. Benchimol, A. Tzakis, J. Gugenheim, X. Hébuterne

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A 34-year-old-man with short-bowel syndrome received an isolated small bowel graft. On postoperative day (POD) 11, ileal biopsy specimen demonstrated mild to moderate rejection that did not respond to corticosteroid bolus therapy. On POD 14, endoscopy and histologic examination revealed exfoliative rejection that was not controlled after 14 days of therapy with thymoglobulin. On POD 95, the patient underwent surgery again because of intestinal obstruction. The graft was removed 6 months after transplantation because of continuous severe abdominal pain with weight loss. After enterectomy, the patient developed multiple-organ failure and died on POD day 8. This case underlines the severity of exfoliative rejection and suggests that early enterectomy be performed when the diagnosis is made, before deterioration of clinical status and development of infectious and nutritional complications.

Original languageEnglish (US)
Pages (from-to)100-102
Number of pages3
JournalTransplantation proceedings
Volume42
Issue number1
DOIs
StatePublished - Jan 1 2010

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Fingerprint Dive into the research topics of 'Outcome of Exfoliative Rejection After Isolated Intestinal Transplantation in an Adult: Case Report'. Together they form a unique fingerprint.

Cite this