Orthotopic ileal neobladder reconstruction after renal transplant

T. Cooke, G. Ciancio, G. W. Burkeb, Mark S Soloway, M. Manoharan

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Radical cystectomy and urinary diversion is an effective curative treatment for muscle invasive bladder cancer. The orthotopic ileal neobladder has become a favorable choice of urinary diversion as it offers superior quality of life, cosmetic outcome and the potential for normal voiding. We treated two patients with bladder cancer who previously underwent renal transplant for end-stage renal disease. Radical cystectomy and orthotopic ileal neobladder reconstruction was performed in both patients. One patient had two renal transplants and underwent transplant nephrectomy at the time of cystectomy. In the other patient, the native kidneys were still present and the ureters were anastomosed to the neobladder. There is excellent function of the neobladder. There were no increased complications seen in these patients. Our cases demonstrate that an orthotopic ileal neobladder is safe and feasible after renal transplant and should be offered to these patients.

Original languageEnglish (US)
Pages (from-to)2630-2633
Number of pages4
JournalAmerican Journal of Transplantation
Issue number11
StatePublished - Nov 1 2007


  • Bladder cancer
  • Orthotopic neobladder
  • Transplant nephrectomy
  • Urinary diversion
  • Urothelial cancer

ASJC Scopus subject areas

  • Immunology


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