Organ culture of the 16th gestation day mouse labyrinth: A model suggestion for pre- and post-partum development

M. Anniko, T. R. Van de Water, H. Nordemar

Research output: Contribution to journalArticle

20 Scopus citations


The 16th day mouse embryo inner ear was ex-planted and cultured "in vitro" for 6 days, which corresponds to 1 day post-partum development "in vivo" A normal development occurred both when the inner ear anlage was divided into a vestibular and a cochlear portion and when it was cultured as a whole. The present model system may provide a helpful tool in the study of both normal development and inner ear pathology.

Original languageEnglish (US)
Pages (from-to)52-55
Number of pages4
JournalActa Oto-Laryngologica
Issue number1-6
StatePublished - Jan 1 1978


ASJC Scopus subject areas

  • Otorhinolaryngology

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