Organ culture of the 16th gestation day mouse labyrinth: A model suggestion for pre- and post-partum development

M. Anniko; T. R. Van de Water; H. Nordemar

doi:10.3109/00016487809124719

Organ culture of the 16th gestation day mouse labyrinth: A model suggestion for pre- and post-partum development

M. Anniko, T. R. Van de Water, H. Nordemar

Otolaryngology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The 16th day mouse embryo inner ear was ex-planted and cultured "in vitro" for 6 days, which corresponds to 1 day post-partum development "in vivo" A normal development occurred both when the inner ear anlage was divided into a vestibular and a cochlear portion and when it was cultured as a whole. The present model system may provide a helpful tool in the study of both normal development and inner ear pathology.

Original language	English (US)
Pages (from-to)	52-55
Number of pages	4
Journal	Acta Oto-Laryngologica
Volume	86
Issue number	1-6
DOIs	https://doi.org/10.3109/00016487809124719
State	Published - 1978

ASJC Scopus subject areas

Otorhinolaryngology

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abstract = "The 16th day mouse embryo inner ear was ex-planted and cultured {"}in vitro{"} for 6 days, which corresponds to 1 day post-partum development {"}in vivo{"} A normal development occurred both when the inner ear anlage was divided into a vestibular and a cochlear portion and when it was cultured as a whole. The present model system may provide a helpful tool in the study of both normal development and inner ear pathology.",

author = "M. Anniko and {Van de Water}, {T. R.} and H. Nordemar",

note = "Funding Information: This work was supported by grants from Karolinska Institutet, Swedish Medical Research Council (grant no. 12X-720), the National Institute of Health (no. NS 08365) &adt he Deafness Research Foundation.",

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AU - Nordemar, H.

N1 - Funding Information: This work was supported by grants from Karolinska Institutet, Swedish Medical Research Council (grant no. 12X-720), the National Institute of Health (no. NS 08365) &adt he Deafness Research Foundation.

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N2 - The 16th day mouse embryo inner ear was ex-planted and cultured "in vitro" for 6 days, which corresponds to 1 day post-partum development "in vivo" A normal development occurred both when the inner ear anlage was divided into a vestibular and a cochlear portion and when it was cultured as a whole. The present model system may provide a helpful tool in the study of both normal development and inner ear pathology.

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Organ culture of the 16th gestation day mouse labyrinth: A model suggestion for pre- and post-partum development

Abstract

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