Oral anticoagulation in patients with cardiomyopathy or heart failure in sinus rhythm

P. Pullicino, J. L.P. Thompson, J. P. Mohr, R. L. Sacco, R. Freudenberger, B. Levin, S. Homma

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

Background: Despite many prospective randomized studies defining the benefits of anticoagulation in atrial fibrillation (AF), there have been no adequate studies in cardiomyopathy (CM) in sinus rhythm. Methods: We review the current knowledge of the risk of stroke in CM, left ventricular systolic dysfunction and heart failure as well as the indications for antithrombotic agents and compare this with AF. Results: The current knowledge of risk factors for stroke and indications for antithrombotic agents in CM is similar to that of AF prior to the treatment studies of the 1980s-1990s. Conclusion: Prospective randomized trial data are urgently needed to determine the role of antithrombotic drugs in CM.

Original languageEnglish (US)
Pages (from-to)322-327
Number of pages6
JournalCerebrovascular Diseases
Volume26
Issue number3
DOIs
StatePublished - Sep 1 2008

Keywords

  • Atrial fibrillation
  • Heart failure, anticoagulation
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Pullicino, P., Thompson, J. L. P., Mohr, J. P., Sacco, R. L., Freudenberger, R., Levin, B., & Homma, S. (2008). Oral anticoagulation in patients with cardiomyopathy or heart failure in sinus rhythm. Cerebrovascular Diseases, 26(3), 322-327. https://doi.org/10.1159/000149581