Oral and maxillofacial surgeons' role in the first successful modified osteo-odonto-keratoprosthesis performed in the United States

Yoh Sawatari, Victor L. Perez, Jean Marie Parel, Eduardo Alfonso, Giancarlo Falcinelli, Johnny Falcinelli, Robert E. Marx

Research output: Contribution to journalArticle

8 Scopus citations


Corneal disease constitutes the second most common cause of blindness 1 and often leads to corneal damage or scarring. Several corneal scarring is a complex and difficult condition for ophthalmologists to manage. In the most severe cases, the scarring is accompanied by excessive dryness and keratinization of the ocular surface. Certain etiologies, including Stevens-Johnson syndrome, cicatricial pemphigoid, Lyell's syndrome, and chemical trauma to the surface of the eye, are responsible for the most severe cases.2 Traditional allogeneic corneal transplantation is not effective because of the significant scarring and dryness of the eye. To allow light and images to be focused on the retina, a keratoprosthesis is required to position a lens on the surface of the eye. One of the oldest and most effective types of keratoprosthesis, the osteo-odonto-keratoprosthesis (OOKP), was first described and documented in 1963 by Strampelli3,4 and subsequently modified by Falcinelli et al.2 The modified OOKP (MOOKP) is a unique prosthesis consisting of a lens fabricated from a polymethylmethacrylate (PMMA) cylinder and cemented to an autogenous graft composed of tooth and bone, traditionally termed the osteo-odonto lamina. In this context, lamina refers to a thin rectangular plate of tooth and bone (Fig 1). The MOOKP involves 4 procedures performed in 3 surgical stages.

Original languageEnglish (US)
Pages (from-to)1750-1756
Number of pages7
JournalJournal of Oral and Maxillofacial Surgery
Issue number6
StatePublished - Jun 1 2011


ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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