Optimizing skin grafting using hair- derived skin grafts: The healing potential of hair follicle pluripotent stem cells

Joshua D. Fox, Katherine L. Baquerizo-Nole, Freya Van Driessche, Elizabeth Yim, Bernard Nusbaum, Francisco Jimenez, Robert Kirsner

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Background. A man in his 60s with recurrent venous leg ulcers (VLUs) presented with an 18-month history of a VLU on his medial left leg measuring 59.3 cm2. He had been treated with multi- component compression bandages without significant decrease in ulcer size. Given the ulcergs size, refractory nature, and history of recurrence, the authors sought to optimize the patientgs healing. Methods. Approximately 23% of the total wound was treated using punch grafts (PGs) harvested from different locations on the body based on hair density using the "stick and placeg" method. Results. One month later, a 56% reduction in ulcer size was observed, espe- cially in the area that received hair-bearing skin. Conclusion. Punch grafts from hair-bearing skin are a viable source of follicular stem cells and may be superior to PG from nonhair-bearing skin for the treatment of chronic wounds.

Original languageEnglish (US)
Pages (from-to)109-111
Number of pages3
JournalWounds
Volume28
Issue number4
StatePublished - Apr 1 2016

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Keywords

  • hair-derived skin graft
  • punch graft
  • venous leg ulcers

ASJC Scopus subject areas

  • Surgery
  • Medical–Surgical

Cite this

Fox, J. D., Baquerizo-Nole, K. L., Van Driessche, F., Yim, E., Nusbaum, B., Jimenez, F., & Kirsner, R. (2016). Optimizing skin grafting using hair- derived skin grafts: The healing potential of hair follicle pluripotent stem cells. Wounds, 28(4), 109-111.