Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: The PREVENCION study

Josefina Medina-Lezama, Catherine A. Pastorius, Humberto Zea-Diaz, Antonio Bernabe-Ortiz, Fernando Corrales-Medina, Oscar Leopoldo Morey-Vargas, Diana Andrea Chirinos, Edgar Mũnoz-Atahualpa, Julio Chirinos-Pacheco, Julio Alonso Chirinos

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

OBJECTIVE - We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults. RESEARCH DESIGN AND METHODS - Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD). RESULTS - Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (κ = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition. CONCLUSIONS - Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.

Original languageEnglish (US)
Pages (from-to)1385-1388
Number of pages4
JournalDiabetes Care
Volume33
Issue number6
DOIs
StatePublished - Jun 2010
Externally publishedYes

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Hispanic Americans
Carotid Intima-Media Thickness
Waist Circumference
National Heart, Lung, and Blood Institute (U.S.)
Cardiovascular Diseases
American Heart Association
Vascular Diseases
Research Design
Abdominal obesity metabolic syndrome

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Cite this

Medina-Lezama, J., Pastorius, C. A., Zea-Diaz, H., Bernabe-Ortiz, A., Corrales-Medina, F., Morey-Vargas, O. L., ... Chirinos, J. A. (2010). Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: The PREVENCION study. Diabetes Care, 33(6), 1385-1388. https://doi.org/10.2337/dc09-2353

Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics : The PREVENCION study. / Medina-Lezama, Josefina; Pastorius, Catherine A.; Zea-Diaz, Humberto; Bernabe-Ortiz, Antonio; Corrales-Medina, Fernando; Morey-Vargas, Oscar Leopoldo; Chirinos, Diana Andrea; Mũnoz-Atahualpa, Edgar; Chirinos-Pacheco, Julio; Chirinos, Julio Alonso.

In: Diabetes Care, Vol. 33, No. 6, 06.2010, p. 1385-1388.

Research output: Contribution to journalArticle

Medina-Lezama, J, Pastorius, CA, Zea-Diaz, H, Bernabe-Ortiz, A, Corrales-Medina, F, Morey-Vargas, OL, Chirinos, DA, Mũnoz-Atahualpa, E, Chirinos-Pacheco, J & Chirinos, JA 2010, 'Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: The PREVENCION study', Diabetes Care, vol. 33, no. 6, pp. 1385-1388. https://doi.org/10.2337/dc09-2353
Medina-Lezama, Josefina ; Pastorius, Catherine A. ; Zea-Diaz, Humberto ; Bernabe-Ortiz, Antonio ; Corrales-Medina, Fernando ; Morey-Vargas, Oscar Leopoldo ; Chirinos, Diana Andrea ; Mũnoz-Atahualpa, Edgar ; Chirinos-Pacheco, Julio ; Chirinos, Julio Alonso. / Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics : The PREVENCION study. In: Diabetes Care. 2010 ; Vol. 33, No. 6. pp. 1385-1388.
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