Optical patient interface in femtosecond laser-assisted cataract surgery: Contact corneal applanation versus liquid immersion

Jonathan H. Talamo, Philip Gooding, David Angeley, William W. Culbertson, Georg Schuele, Daniel Andersen, George Marcellino, Emma Essock-Burns, Juan Batlle, Rafael Feliz, Neil J. Friedman, Daniel Palanker

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Purpose: To compare 2 optical patient interface designs used for femtosecond laser-assisted cataract surgery. Setting: Optimedica Corp., Santa Clara, California, USA, and Centro Laser, Santo Domingo, Dominican Republic. Design: Experimental and clinical studies. Methods: Laser capsulotomy was performed during cataract surgery with a curved contact lens interface (CCL) or a liquid optical immersion interface (LOI). The presence of corneal folds, incomplete capsulotomy, subconjunctival hemorrhage, and eye movement during laser treatment were analyzed using video and optical coherence tomography. The induced rise of intraocular pressure (IOP) was measured in porcine and cadaver eyes. Results: Corneal folds were identified in 70% of the CCL cohort; 63% of these had areas of incomplete capsulotomies beneath the corneal folds. No corneal folds or incomplete capsulotomies were identified in the LOI cohort. The mean eye movement during capsulotomy creation (1.5 sec) was 50 μm with a CCL and 20 μm with an LOI. The LOI cohort had 36% less subconjunctival hemorrhage than the CCL cohort. During suction, the mean IOP rise was 32.4 mm Hg ± 3.4 (SD) in the CCL group and 17.7 ± 2.1 mm Hg in the LOI group. Conclusions: Curved contact interfaces create corneal folds that can lead to incomplete capsulotomy during laser cataract surgery. A liquid interface eliminated corneal folds, improved globe stability, reduced subconjunctival hemorrhage, and lowered IOP rise. Financial Disclosure: Drs. Talamo, Culbertson, Batlle, Feliz, and Palanker are consultants to and Messrs. Gooding, Angeley, Schuele, Marcellino, and Andersen, and Ms. Essock-Burns are employees of Optimedica Corp., Sunnyvale, California, USA.

Original languageEnglish (US)
Pages (from-to)501-510
Number of pages10
JournalJournal of cataract and refractive surgery
Issue number4
StatePublished - Apr 1 2013

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems


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