Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding

Joseph M. Slocik; Zhifeng Kuang; Marc Knecht; Rajesh R. Naik

doi:10.1002/cphc.201600670

Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding

Joseph M. Slocik, Zhifeng Kuang, Marc Knecht, Rajesh R. Naik

Chemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications. To achieve this level of control, an azobenzene-based optical switch is added to nanoparticle-binding peptides in order to switch peptide conformation and attenuate binding affinity to gold surfaces via binding and dissociation of peptides.

Original language	English (US)
Journal	ChemPhysChem
DOIs	https://doi.org/10.1002/cphc.201600670
State	Accepted/In press - 2016

Keywords

Azobenzene
Bionanotechnology
Gold nanoparticles
Peptides
Phage display

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Physical and Theoretical Chemistry

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