Optic Pit Maculopathy: Clinical Features and Management Options

Prashanth G. Iyer, Harry W. Flynn, Kenneth C. Fan, Audina M. Berrocal, Raquel Goldhardt

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: In this article, we review the pathogenesis, clinical features, imaging modalities, and latest management options for optic pit maculopathy (OPM). Recent Findings: The pathogenesis of OPM remains to be unclear, but imaging tools such as optical coherence tomography (OCT) and OCT angiography are enhancing our knowledge. Observation continues to be the best management strategy for patients with good visual acuity, and many cases have demonstrated spontaneous resolution. For more advanced, progressive vision loss, treatment options involving vitrectomy can be considered and discussed with the patient. Supplementary techniques to vitrectomy have been reported in small studies with relative success such as glial tissue peeling, inverted internal limiting membrane flap, optic pit plugging, and retinal fenestration. Summary: While there are multiple treatment options available for OPM, there is no consensus on the technique and surgical timing. Individual patient factors and the risks-benefits of treatment must be taken into account in guiding management. Larger clinical trials will further assist in decision-making for treating OPM.

Original languageEnglish (US)
JournalCurrent Ophthalmology Reports
StateAccepted/In press - 2021


  • Congenital optic pit
  • Lamina cribosa
  • Maculopathy
  • Optic pit
  • Optic pit maculopathy
  • Pars plana vitrectomy

ASJC Scopus subject areas

  • Ophthalmology


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