Optic nerve: Scanning laser polarimetry

Clinton W. Sheets, David S. Greenfield

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Scanning laser polarimetry (SLP) is a confocal scanning laser ophthalmoscope with an integrated polarimeter that measures the amount of retardation (phase shift) of a polarized, near-infrared laser beam as it passes through the retinal nerve fiber layer (RNFL) [6, 12, 18-22]. The RNFL is made of highly ordered parallel axon bundles. The axons contain microtubules, cylindrical intracellular organelles with diameters smaller than the wavelength of light. The highly ordered structure of the microtubules is the source of RNFL birefringence [20]. Different birefringence patterns are detected when the RNFL is healthy versus atrophied from glaucoma.

Original languageEnglish (US)
Title of host publicationPearls of Glaucoma Management
PublisherSpringer Berlin Heidelberg
Pages35-43
Number of pages9
ISBN (Print)9783540682387
DOIs
StatePublished - Dec 1 2010

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sheets, C. W., & Greenfield, D. S. (2010). Optic nerve: Scanning laser polarimetry. In Pearls of Glaucoma Management (pp. 35-43). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-68240-0_4