Opioids and the skin: "Itchy" perspectives beyond analgesia and abuse

Martin Schmelz; Ralf Paus

doi:10.1038/sj.jid.5700634

Opioids and the skin: "Itchy" perspectives beyond analgesia and abuse

Martin Schmelz, Ralf Paus

Research output: Contribution to journal › Comment/debate › peer-review

6 Scopus citations

Abstract

Opioids are intimately linked to central pain inhibition and their abuse potential. Thus, peripheral opioid receptors in the skin have been studied initially with a focus on their peripheral analgesic properties. Recent results, however, clearly indicate that opioids play a specific role in skin homeostasis by modulating keratinocyte differentiation, wound healing, and inflammatory responses.

Original language	English (US)
Pages (from-to)	1287-1289
Number of pages	3
Journal	Journal of Investigative Dermatology
Volume	127
Issue number	6
DOIs	https://doi.org/10.1038/sj.jid.5700634
State	Published - Jun 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

Access to Document

10.1038/sj.jid.5700634

Fingerprint Dive into the research topics of 'Opioids and the skin: "Itchy" perspectives beyond analgesia and abuse'. Together they form a unique fingerprint.

Cite this

@article{8abd5960683f4faf99be8f53b7022eae,

title = "Opioids and the skin: {"}Itchy{"} perspectives beyond analgesia and abuse",

abstract = "Opioids are intimately linked to central pain inhibition and their abuse potential. Thus, peripheral opioid receptors in the skin have been studied initially with a focus on their peripheral analgesic properties. Recent results, however, clearly indicate that opioids play a specific role in skin homeostasis by modulating keratinocyte differentiation, wound healing, and inflammatory responses.",

author = "Martin Schmelz and Ralf Paus",

year = "2007",

month = jun,

doi = "10.1038/sj.jid.5700634",

language = "English (US)",

volume = "127",

pages = "1287--1289",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

publisher = "Nature Publishing Group",

number = "6",

}

TY - JOUR

T1 - Opioids and the skin

T2 - "Itchy" perspectives beyond analgesia and abuse

AU - Schmelz, Martin

AU - Paus, Ralf

PY - 2007/6

Y1 - 2007/6

N2 - Opioids are intimately linked to central pain inhibition and their abuse potential. Thus, peripheral opioid receptors in the skin have been studied initially with a focus on their peripheral analgesic properties. Recent results, however, clearly indicate that opioids play a specific role in skin homeostasis by modulating keratinocyte differentiation, wound healing, and inflammatory responses.

AB - Opioids are intimately linked to central pain inhibition and their abuse potential. Thus, peripheral opioid receptors in the skin have been studied initially with a focus on their peripheral analgesic properties. Recent results, however, clearly indicate that opioids play a specific role in skin homeostasis by modulating keratinocyte differentiation, wound healing, and inflammatory responses.

UR - http://www.scopus.com/inward/record.url?scp=34248599024&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248599024&partnerID=8YFLogxK

U2 - 10.1038/sj.jid.5700634

DO - 10.1038/sj.jid.5700634

M3 - Comment/debate

C2 - 17502859

AN - SCOPUS:34248599024

VL - 127

SP - 1287

EP - 1289

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

IS - 6

ER -