Opioids and the skin: "Itchy" perspectives beyond analgesia and abuse

Martin Schmelz, Ralf Paus

Research output: Contribution to journalComment/debatepeer-review

9 Scopus citations


Opioids are intimately linked to central pain inhibition and their abuse potential. Thus, peripheral opioid receptors in the skin have been studied initially with a focus on their peripheral analgesic properties. Recent results, however, clearly indicate that opioids play a specific role in skin homeostasis by modulating keratinocyte differentiation, wound healing, and inflammatory responses.

Original languageEnglish (US)
Pages (from-to)1287-1289
Number of pages3
JournalJournal of Investigative Dermatology
Issue number6
StatePublished - Jun 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology


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