Opioid use patterns in patients with head and neck cancer receiving radiation therapy: Single-institution retrospective analysis characterizing patients who did not require opioid therapy

Benjamin J. Rich, Leif Erik D. Schumacher, Zoukaa B. Sargi, Melissa Masforroll, Deukwoo Kwon, Wei Zhao, Maria A. Rueda-Lara, Laura M. Freedman, Nagy Elsayyad, Stuart E. Samuels, Matthew C. Abramowitz, Michael A. Samuels

Research output: Contribution to journalArticlepeer-review

Abstract

Background: We had previously analyzed the variables that determine the rates of opioid use at 1-year postradiotherapy in patients with head and neck cancer. Here we analyze the variables associated with opioid abstinence during and in the 12 months after radiotherapy at our institution. Methods: We identified a cohort of patients with head and neck cancer who received radiotherapy as part of curative treatment at our institution. Logistic regression analyses were performed to determine socioeconomic and clinical factors associated with opioid abstinence. Results: The cohort included 376 patients. On multivariable analysis, patients from an upper-income class (p = 0.004), black race (p = 0.004), older (p = 0.008), with dependent children (p < 0.001) or receiving surgery (p = 0.002) were more likely to abstain from opioids, while patients using analgesic mouthwash (p = 0.009) or higher pain scale (p = 0.002) were less likely. Conclusion: Socioeconomic and treatment characteristics are associated with opioid abstinence during and following radiation treatment in patients with head and neck cancer.

Original languageEnglish (US)
Pages (from-to)2973-2984
Number of pages12
JournalHead and Neck
Volume43
Issue number10
DOIs
StatePublished - Oct 2021

Keywords

  • analgesics
  • cancer
  • head and neck neoplasms
  • opioids
  • radiotherapy

ASJC Scopus subject areas

  • Otorhinolaryngology

Fingerprint

Dive into the research topics of 'Opioid use patterns in patients with head and neck cancer receiving radiation therapy: Single-institution retrospective analysis characterizing patients who did not require opioid therapy'. Together they form a unique fingerprint.

Cite this