Opiate detoxification protocols: A clinical manual

David A Fishbain, H. L. Rosomoff, R. Cutler, R. S. Rosomoff

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The purpose of any opiate detoxification protocol is to minimize or eliminate the signs and symptoms associated with opiate withdrawal, thereby decreasing the chances of relapse to opiate dependence. In the last few years, because of the development of new medications such as clonidine, for the treatment of opiate withdrawal, a number of new protocols have been developed. Four different types of protocols are reviewed and outlined: methadone substitution/detoxification, codeine or other opiate substitution detoxification, opiate of choice detoxification, and buprenorphine substitution detoxification. In addition, six protocols utilizing clonidine are presented, including a protocol utilizing opiate antagonist precipitated withdrawal. Finally, two protocols that utilize naltrexone are outlined, and adjunct medications potentially useful in opiate detoxification are reviewed. Some suggestions for the treatment of drug-seeking behavior during detoxification and the advantages and disadvantages of the various protocols are summarized.

Original languageEnglish
Pages (from-to)53-65
Number of pages13
JournalAnnals of Clinical Psychiatry
Volume5
Issue number1
StatePublished - Jan 1 1993

Fingerprint

Opiate Alkaloids
Clinical Protocols
Clonidine
Drug-Seeking Behavior
Opioid-Related Disorders
Codeine
Buprenorphine
Naltrexone
Methadone
Signs and Symptoms
Recurrence

Keywords

  • Clonidine
  • Detoxification
  • Opiates
  • Protocols

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Fishbain, D. A., Rosomoff, H. L., Cutler, R., & Rosomoff, R. S. (1993). Opiate detoxification protocols: A clinical manual. Annals of Clinical Psychiatry, 5(1), 53-65.

Opiate detoxification protocols : A clinical manual. / Fishbain, David A; Rosomoff, H. L.; Cutler, R.; Rosomoff, R. S.

In: Annals of Clinical Psychiatry, Vol. 5, No. 1, 01.01.1993, p. 53-65.

Research output: Contribution to journalArticle

Fishbain, DA, Rosomoff, HL, Cutler, R & Rosomoff, RS 1993, 'Opiate detoxification protocols: A clinical manual', Annals of Clinical Psychiatry, vol. 5, no. 1, pp. 53-65.
Fishbain DA, Rosomoff HL, Cutler R, Rosomoff RS. Opiate detoxification protocols: A clinical manual. Annals of Clinical Psychiatry. 1993 Jan 1;5(1):53-65.
Fishbain, David A ; Rosomoff, H. L. ; Cutler, R. ; Rosomoff, R. S. / Opiate detoxification protocols : A clinical manual. In: Annals of Clinical Psychiatry. 1993 ; Vol. 5, No. 1. pp. 53-65.
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